AACR2026-Cancer-Reaesrch

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Cell Biology, Proteomics, Histology, Molecular Biology, Small Molecules, Lab Supplies & AntibodiesHighly-selected products for Cancer Research

 

This web page introduces Diagnocine's unique and selected line-up for Cancer Research.
You can find reagents, kits, and lab supplies that are just right for you!

 


Cell Biology

LipiDye™ RED

Fluorescense lifetime imaging of LipiDye RED

LipiDye™ RED is a reagent that enables high-sensitivity red-fluorescent imaging of lipid droplets in live cells.
- Selective staining of lipid droplets (LD) with high S/N ratio
- Detects small lipid droplets ( 1 um) in non-adipocyte cells
- Compatible with live/fixed cells & STED microscopy
-Analysis of the lipid composition of individual lipid dropletsand the progression of lipid hydrolysis by using fluorescence lifetime imaging.

FAOBlue™

FAOBlue in HepG2 (-FAO inhibitor) FAOBlue in HepG2 (+FAO inhibitor)
 

Fatty acid beta-oxidation detection dye in live cells
FAO activity of fatty acid beta-oxidation in living cells can be easily measured by the fluorescence imaging method.
It can be widely applied to comparative evaluation of β-oxidation activity of fatty acids in different cell types, search for compounds that promote or inhibit β-oxidation activity, and basic research on enzymes involved in β-oxidation.

PolyamineRED™

PolyamineRED cell

Novel polyamine specific detection dye in live cells as a potential cancer marker.
It is suitable for detection or semi-quantitative analysis of intracellular polyamines.

AcroleinRED™

Acrolein Increase in HUVECs

ONE & ONLY simple method for acrolein detection in live cell w/o cell disruption / antibodies.
This reagent does not react with other unsaturated aldehydes or lipid metabolites etc., and enables easy detection and relative quantification of endogenous acrolein or acrolein produced by external stimuli in living cells.

HydroCell® Flask, Low Cell Binding Cultureware

 Overview of HydroCell surface HydroCell Flask
 

Super hydrophilic polymer is immobilized to the surface of the culture ware at nano-thickness.
For formation of embryoid bodies of ES cells in culture, anchorage-independent colonies, differentiation such as cartilage (spheroid formation), culture & storage of macrophage / immune cellsscreening of anti-cancer drugs (replacement for soft agar assays), etc.

AZ PRESERVER™, Novel Hypothermic Storage/Transportation Solution

AZ PRESERVER Graph

Minimizes cellular stress during refrigerated storage and enables superior preservation performance.
Simply replace the culture medium of mammalian cells or organoids with AZ PRESERVER - no complicated procedures required.

Ideal for:
- Short-term storage and transportation of cells or organoids that are difficult to cryopreserve.
Direct transplantation of organoids to animals

 

Proteomics

SignalBooster Neo - Signal Enhancer for Western Blot & ELISA

SignalBooster-Neo

Try Signal Booster Neo to get higher signals for western blotting, ELISA, etc.
By simply diluting antibodies with Signal Boosters, signals increase and background decrease.
Compatible for phosphoprotein detection or for any ELISA. Protein-free composition contributes to no interference by proteins in the reagent.

NanoDisc BD kit - Membrane Protein Expression on NanoDisc

NanoDisc-BD

* Available in US only.

Try NanoDisc BD Kit is a set of reagents necessary for NanoDisc synthesis for membrane protein with good quality and yield.
This kit takes advantage of the benefits of the wheat cell-free synthesis system and combines WEPRO7240ND, a wheat germ extract optimized for Nanodisc synthesis, with the BD method, which has a proven track record in proteoliposome synthesis, and a new synthesis method (patent pending) that co-expresses mRNA for MSP protein and mRNA for the target membrane protein.

 

Histology

HistoBright - For Deep-Imaging and Spatial Structural Analysis of Tissue Blocks

HistoBright

HistoBright is an environment-responsive membrane-staining fluorescent dye which can be exited by the two photon laser.
It has high tissue permeability, and its fluorescent properties change depending on the local structure of the tissue, allowing high-contrast tissue visualization.
Combining tissue clearing techniques with two photon laser microscopy allows deep-imaging and spatial structural analysis of tissue blocks.
The fluorescence characteristics change from green to near-infrared depending on the surrounding environment (Solvatochromic Property).
Both confocal microscopy (recommended excitation laser: 488 nm laser) and two photon microscopy (recommended laser: 960 nm laser) are compatible.

CUBIC - Tissue Clearing Reagent Kit

How To Use

CUBIC enables cellular resolution 3D imaging of entire organs at cellular resolution using Light-Sheet Fluorescence Microscopy (LSFM) or Confocal Laser Scanning Microscopy (CLSM).
- The protocol requires only standard laboratory equipment no specialized equipment like electrophoresis systems is required.
- Highly versatile water-soluble CUBIC tissue clearing kits that have a powerful transparency level.
- Compatible with all organs including the bone. Fluorescent protein signals can be observed after clearing the sample.

 

Molecular Biology

Kaneka Easy DNA Extraction Kit Version2

 Kaneka DNA Extraction Kit  Protocol of easy DNA extraction kit  
 
 

This kit can extract template DNA usable for PCR and real-time PCR from biological samples with a 10 minutes operation!
Broad range of sample are compatible with this kit
- Cells, Animal Tissue, Plant, Bacteria, Blood and Feces.

Colored RNA Markers

Colored RNA Markers    Prestain RNA ladder transfred on membrane 
 
 

Prestained RNA Ladder for single-stranded RNA electrophoresis, made with patented technology.
You can monitor separation/transfer status.
The prestain markers can be transferred to a membrane, so transfer efficiency and the membrane orientation in Northern blotting can be checked.

Taq DNA Polymerase

Taq DNA Polymerase

Best Price!
  Comparable performance as Leading Brands.
  Various formats available, Robust buffer induces maximum enzymatic activity.

Beyond Agarose - Strong gels, clear results

 
 Gels image  Gel strength comparison  
  
 

Beyond Agarose is a newly developed hybrid agarose gel designed as a high performance alternative to conventional low melting point agarose widely used for low molecular-weight DNA separation.

- Good separation of small DNA fragments
- Cost-effective alternative to low-melting agarose
- Strong, flexible gels that resist breaking.
- Ideal and reliable performance for routine DNA analysis.

 

Small Molecules

KRN7000 (α-Gal-Cer) - Natural Killer T (NKT) Cell Activator

alpha-Gal-Cer

KRN7000 exhibits various immunological effects through NKT cell functions including potent antitumor effect.
  Specific ligand for human and mouse NKT cells
  Activates CD1d mediated invariant NKT cells (iNKT cells)
  Validated bioactivity by FCM
  For in-vitro & in vivo use

Blasticidin S

Blasticidin S

Best quality nucleoside antibiotic for the selection of transformants carrying blasticidin-resistance genes.
Useful for establishing iPSCs by CiRA protocol.

TLR9 Agonist D35/K3 (CpG-ODN)

 Cytokine Induction on hPBMC using TLR9 ligand  Cytokine Induction on mouse FL-DC using TLR9 ligand  
 

Immune stimulation of potent and specific human, mouse immune cells, and for animal experiments, offered in vials with high purity.
Endotoxin level is 0.5 EU/mg or less.

 

Lab Supplies

BioMasher - Disposable Tissue Homogenizer

 
BioMasher I, II & III BioMasher SP     BioMasher V
 
 

BioMasher series are disposable homogenizers for easy and convenient grind.
You can choose appropriate BioMasher suitable for your sample size and type.

FUNABOX Smartphone Gel Imaging System

FUNABOX

A set of darkroom hood and smartphone attachment adapter (width adjustment range 5.7 cm to 10.5 cm).
Transilluminator is sold separately. FUNA LED Mini Transilluminator is suitable, see below.

FUNA LED Mini Transilluminator

FUNA LED Mini Transilluminator F-LMT505
 

24 High-intensity LEDs with forced-air cooling for powerful, stable illumination.

 

Antibodies

Antibody for Animal PD-L1

- Rat monoclonal antibody
- Isotype : IgG2a κ
- Reactivity : Cow / Dog / Horse / Pig / Sheep / Goat / Buffalo
- Clone : 6C11-3A11
- For IHC / FCM

MUC1 Antibody (014E)

MUC1 Antibody (014E)

- Specifically detects scirrhous gastric cancer & pancreatic cancer
- Isotype : IgG1 κ
- Reactivity : Human
- Specificity : Human Mucin 1
- Clone : 014E
- For IHC / Western blot

Lumican Polyclonal Antibody

Lumican Polyclonal Antibody

↑IHC image of Bowen's disease patient tissue.
Lumican expression is detected in cytoplasm of cancer cells at epidermis.


- Clear stain of tumor part and stromal component in cancer tissues
Pathologically validated
- Host : Rabbit
- For Human and Rat
- For IHC / Western blot

 

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