Benastatin C
Product#: FNK-00380
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Benastatin C
Specifications
Code No: FNK-00380
Size: 1mg
CAS#: 150151-88-5
Molecular Formula: C29H28O5
Molecular Weight: 456.538
Source: Streptomyces sp. MI384-DF12
Appearance: Brownish-yellow powder
Purity: > 90%(HPLC)
Long Term Storage: at -20 °C
Solubility: Soluble in DMSO, MeOH, Acetone, EtOAc. Insoluble in H2O.
Application NotesSize: 1mg
CAS#: 150151-88-5
Molecular Formula: C29H28O5
Molecular Weight: 456.538
Source: Streptomyces sp. MI384-DF12
Appearance: Brownish-yellow powder
Purity: > 90%(HPLC)
Long Term Storage: at -20 °C
Solubility: Soluble in DMSO, MeOH, Acetone, EtOAc. Insoluble in H2O.
Benastatin C is isolated from the culture broth of Streptomyces sp. MI384-DF12 as an inhibitor of glutathione S-transferase (GST).1
It shows considerable activities (IC50: 0.16 µg/mL) against human pi class GST (GSTπ).1 Benactatin C has inhibitory activity against esterase obtained from hog pancreas lipase (IC50: 10.0 µg/mL) and has excellent stimulatory activities on the murine lymphocyte blastogenesis.
It shows considerable activities (IC50: 0.16 µg/mL) against human pi class GST (GSTπ).1 Benactatin C has inhibitory activity against esterase obtained from hog pancreas lipase (IC50: 10.0 µg/mL) and has excellent stimulatory activities on the murine lymphocyte blastogenesis.
References
- Benastatins C and D, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. Production, isolation, structure determination and biological activities. Aoyama T, et al. J Antibiot. 1993 46(5) 712-718.
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