What makes the filtration process superior to standard 0.22 micron filtered media?

Standard 0.22 micron filtration does not retain mycoplasma-sized particles (0.2-0.3 micron) or subvisible particulates that accumulate in microchannels. FluxMPS uses four sequential passes reaching 0.04 micron, delivering approximately 5x lower particulate counts per USP less than 788 Method 1.

Why does DCP-DM12H-T1X include 15 mM HEPES alongside sodium bicarbonate, and how do I use it?

The dual-buffer system (15 mM HEPES plus 14 mM sodium bicarbonate) provides stable pH control across a range of CO2 conditions, reducing dependence on precise incubator CO2 while remaining compatible with standard 5 percent CO2 culture. Glucose (3151 mg/L), L-glutamine (365 mg/L), and sodium pyruvate (110 mg/L) are provided at standard DMEM/F-12 levels and typically require no further supplementation.

Does DCP-DM12H-T1X require a CO2 incubator?

This formulation is HEPES-buffered with reduced sodium bicarbonate, reducing CO2 dependency. Standard 5 percent CO2 incubation remains compatible, and the medium tolerates brief ambient-CO2 handling better than bicarbonate-only formulations.

FluxMPS Dulbecco's Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid

Q: Can DCP-DM12H-T1X be supplemented with serum, growth factors, or other components?

Yes. Supplement with FBS (5-20 percent), growth factors, antibiotics, or other additives per standard practice. Filter serum-containing and protein-containing supplements through a 0.2 micron low-protein-binding PES or PVDF membrane before addition; do not use a 0.04 micron membrane. Add supplements immediately before use.

Q: What endotoxin level should I expect, and how is it verified?

Endotoxin is controlled per manufacturing batch by LAL assay per USP less than 85 BET (assay sensitivity 0.005 EU/mL). Release specification: less than 0.05 EU/mL. Every batch is tested before release; results are reported on the Certificate of Analysis, available from support@diagnocine.com.

Q: Is a Certificate of Analysis (CoA) available, and what does it contain?

Yes. A batch-specific CoA is available for every shipment and includes appearance, pH (USP less than 791), osmolality (USP less than 785), endotoxin (USP less than 85 BET), sterility (USP less than 71), particulate matter (USP less than 788 Method 1), raw material traceability, manufacturing date, and authorized release signatures. Request via support@diagnocine.com.

ISO 13485 Certified Manufacturing

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid

L-Glutamine Sodium Bicarbonate Phenol Red HEPES Calcium Magnesium Glucose Sodium Pyruvate

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid is a Microfluidics Suitable, quadruple-stage ultra-filtered (0.1 µm ×2 + 0.04 µm ×2) 1X liquid cell culture medium engineered for organ-on-a-chip (OoC), tissue-on-a-chip (ToC), and microphysiological system (MPS) applications. A quadruple-stage train (0.1 µm ×2 + 0.04 µm ×2) reaches a 0.04 µm final cut-off, five times finer than the 0.22 µm membranes used for conventional sterile filtration.

Quadruple-stage filtration train: 0.1 µm (Prefiltration I & II) + 0.04 µm (Final filtration I & II — Polish), reaching a 0.04 µm final cut-off
Endotoxin release specification: < 0.05 EU/mL (LAL assay, USP <85> BET), controlled per manufacturing batch
DMEM/F-12 (1:1) base formulation supplemented with 15 mM HEPES; pH 7.4 (USP <791>)
Dual-buffered system: sodium bicarbonate (1200 mg/L) plus 15 mM HEPES for buffering stability
Prepared with Ultrapure Type 1 water (18.2 MΩ·cm, ASTM D1193 / ISO 3696)
Manufactured under an ISO 13485:2016 quality management system with aseptic fill & finish
Mycoplasma risk mitigated via 0.1 µm mycoplasma-retentive filtration (not tested per lot)
Custom formulations available — pH, glucose, salts, HEPES, and nutrient composition on request

DCP-DM12H-T1X |Sizes: 500 mL, 1000 mL |Cell Culture Media

UNSPSC: 41116155 | Commodity: Molecular biology and cell culture growth media | (UNv260801)

Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid

Glucose3151 mg/L (3.151 g/L)
L-Glutamine365 mg/L
Sodium Pyruvate110 mg/L
HEPES3574.5 mg/L (15 mM)
pH (USP <791>)7.4
Osmolality (USP <785>)Contact for specification
Endotoxin (USP <85>)< 0.05 EU/mL
Filtration0.1 µm ×2 + 0.04 µm ×2
Storage2–8°C, protect from light
Shelf Life12 months from date of manufacture, unopened

ISO 13485:2016 USP <85> <785> <788> RUO

Why FluxMPS™

Engineered where standard media fails

Conventional 0.22 µm-filtered media carry mycoplasma-sized particulates (0.2–0.3 µm), subvisible debris, and lot-to-lot particulate variation that accumulates inside microchannels — corrupting biosensor readings and shortening device lifetimes. FluxMPS™ is designed to reduce these risks at the source.

filter_alt

Microchannel-safe purity

0.04 µm final filter retains particles to sub-mycoplasma size; USP <788> Method 1 (light obscuration) particulate compliance verified per lot.

target

Total metabolic control

Defined carbon source (3151 mg/L glucose), 365 mg/L L-glutamine, and 110 mg/L sodium pyruvate for reproducible metabolic flux experiments.

water_drop

Ultrapure-grade water

Prepared with Type 1 water (18.2 MΩ·cm) to ASTM D1193 / ISO 3696 standards, with controlled trace-metal and total organic carbon (TOC) content.

visibility

Low background for imaging

Quadruple-stage filtration reduces particulate background, supporting confocal microscopy, live-cell biosensors, and TEER measurements. Note: this formulation contains phenol red; a phenol-red-free variant is available on request for assays requiring minimal optical background.

science

Rich, stable nutrient profile

Micro-batch precision locks in amino acid and vitamin concentrations for lot-to-lot reproducibility in long-term perfusion studies.

tune

Customization on demand

pH, glucose, salts, HEPES, and full nutrient composition available on request. Contact support@diagnocine.com.

Purity Architecture

Quadruple-stage filtration system

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid is processed through a four-stage serial filtration train reaching a 0.04 µm final cut-off — two paired prefilter + final-filter stages in series, each 0.04 µm final filter protected by its own dedicated 0.1 µm prefilter.

1

0.1 µm Prefiltration I

Removes large particulates and aggregates; protects the first 0.04 µm cartridge and extends filter life.
2

0.04 µm Final filtration I

First 0.04 µm pass; retains sub-micron particulates and microaggregates that pass a 0.22 µm filter.
3

0.1 µm Prefiltration II

Second dedicated prefilter, protecting the second 0.04 µm cartridge from breakthrough.
4

0.04 µm Final filtration II — Polish

Ultimate polishing filter; aseptic fill & finish in a validated ISO Class 5 laminar-flow workstation.

Performance vs. conventional media

Four sequential stages reaching 0.04 µm deliver approximately 5× cleaner media by particulate count compared to single-pass 0.22 µm filtration.

5×

0.04

µm final filter pore size — sub-mycoplasma polishing

Sterility assurance: Every lot undergoes 14-day USP <71> sterility testing. Mycoplasma risk is mitigated via 0.1 µm mycoplasma-retentive filtration (not tested per lot).

Grade: This product is Microfluidics Suitable, filtered to a 0.04 µm final cut-off. It is not an MPS Grade product — that designation is reserved for the 0.01 µm ultra nano-filtered line, which adds 0.02 µm and 0.01 µm stages after the 0.04 µm polish. For applications requiring the 0.01 µm cut-off, contact support@diagnocine.com.

FluxMPS™ Dulbecco's Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid (DCP-DM12H-T1X) Quadruple-stage filtration system: 0.1 μm Prefiltration I, 0.04 μm Final filtration I, 0.1 μm Prefiltration II, 0.04 μm Final filtration II - Polish, for organ-on-a-chip and microfluidic applications by Diagnocine — **Figure 1.** FluxMPS™ Quadruple-stage filtration architecture (0.1 µm ×2 + 0.04 µm ×2).
© Diagnocine® — DCP-DM12H-T1X

Applications

Designed for next-generation cell culture platforms

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid is validated for organ-on-a-chip, metabolic research, live-cell imaging, and primary cell models where particulate contamination and endotoxin variability are unacceptable.

Automated Bioreactors & Robotics

Next-Generation System Uptime

An optional 0.01 µm (10 nm) ultra nano-filtered MPS Grade variant is available for automated bioreactor and robotic perfusion systems requiring the highest particulate exclusion.

Total Particulate Exclusion: 10 nm filtration for nanoscale valve and sensor protection
Valve & Sensor Protection: prevents particulate-induced blockage in precision fluidic systems
Extended Perfusion Stability: maintains flow rate consistency across multi-week automated runs

Inquiry Required: Contact support@diagnocine.com to request the 0.01 µm MPS Grade variant.

Microfluidics

Micro Physiological System (MPS) & Chip

Ultra-filtered formulation supports microchannel integrity and laminar flow in fluidic devices.

OoCToCBoCLoCMPS

Cancer Biology

Warburg Effect & Metabolic Research

Defined carbon source (3151 mg/L glucose) supports precise metabolic flux analysis in cancer cell models.

MCF-7MDA-MB-231HeLaHT-1080

Stem Cell Biology

iPSC-Derived Models

Ultra-filtered formulation supports sensitive iPSC differentiation protocols where endotoxin variability causes off-target effects.

iPSC-NeuronsiPSC-CMiPSC-Hep

Vascular Biology

Endothelial & Primary Cells

Microchannel-safe purity supports endothelial barrier integrity and TEER measurements.

HUVECsBHK-21Primary fibroblasts

Metabolomics

Metabolic Flux Analysis

Chemically defined base enables isotope tracing. Not compatible with Agilent Seahorse XF assays, which require bicarbonate-free, phenol red-free medium; this formulation contains both sodium bicarbonate and phenol red.

¹³C tracingNMR metabolomics

Live-Cell Imaging

Microscopy & Optical Sensing

Low particulate background supports confocal imaging and biosensor integration; phenol red present may contribute to background absorbance in some assays.

ConfocalBiosensorsTEER

Technical Specifications

Lot-release quality parameters

Every production lot of FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid undergoes the quality-release battery below before shipment.

Physical & Chemical Parameters

Parameter	Specification
Formulation	Contains L-Glutamine (365 mg/L), Sodium Bicarbonate (1200 mg/L), Phenol Red (8.63 mg/L), HEPES (3574.5 mg/L / 15 mM), Calcium (as CaCl₂·2H₂O), Magnesium (as MgCl₂·6H₂O + MgSO₄), Glucose (3151 mg/L), Sodium Pyruvate (110 mg/L)
Appearance	Red-colored, clear solution
pH USP <791>	7.4
Osmolality USP <785>	Contact for specification
Glucose	3151 mg/L (3.151 g/L)
L-Glutamine	365 mg/L
Sodium Pyruvate	110 mg/L
Phenol Red	8.630 mg/L (present)

Sterility, Purity & Safety Parameters

Parameter	Specification
Endotoxin USP <85> BET	< 0.05 EU/mL (batch release specification — see Manufacturing & Compliance)
Sterility USP <71>	No growth after 14 days
Mycoplasma	0.1 µm mycoplasma-retentive filtration (not tested per lot)
Particulate USP <788> Method 1	Light obscuration; compliant
Water Purity	Ultrapure Type 1, 18.2 MΩ·cm (ASTM D1193 / ISO 3696)
Manufacturing std. ISO 13485	ISO 13485:2016
Fill environment	ISO Class 5 (Class 100)

Storage, Handling & Logistics

Parameter	Specification
Storage temperature	2–8°C, protected from light
Freeze-thaw	Not recommended
Shelf life	12 months from date of manufacture, unopened
Shipping condition	Cold pack
CO₂ requirement	HEPES-buffered; reduced CO₂ dependence (validate per cell line)

Raw Materials & Regulatory Traceability

Parameter	Specification
Raw material grade	Cell culture / reagent grade
Traceability	Full lot documentation, CoA available
Manufacturing QMS	ISO 13485:2016 certified
UNSPSC	41116155 — Molecular biology and cell culture growth media (UNv260801)
Regulatory alignment	21 CFR Part 820 (QMSR) aligned
Production method	Micro-batch precision manufacturing
Intended use	For Research Use Only (RUO)

Formulation

Full composition (mg/L)

Complete formulation with CAS numbers, reproduced from manufacturer specification (53 total components across three composition tabs: Inorganic Salts, Amino Acids, and Vitamins & Others). Custom compositions available on request.

Component	CAS Number	mg/L
INORGANIC SALTS
Calcium chloride dihydrate	10035-04-8	154.500
Copper sulfate pentahydrate	7758-99-8	0.0013
Disodium hydrogen phosphate	7558-79-4	71.020
Ferric nitrate nonahydrate	7782-61-8	0.050
Ferrous sulfate heptahydrate	7782-63-0	0.417
Magnesium chloride hexahydrate	7791-18-6	61.200
Magnesium sulfate anhydrous	7487-88-9	48.840
Potassium chloride	7447-40-7	311.800
Sodium bicarbonate	144-55-8	1200.000
Sodium chloride	7647-14-5	6996.000
Sodium dihydrogen phosphate monohydrate	10049-21-5	54.300
Zinc sulfate heptahydrate	7446-20-0	0.432

Component	CAS Number	mg/L
AMINO ACIDS
Glycine	56-40-6	18.750
L-Alanine	56-41-7	4.450
L-Arginine hydrochloride	1119-34-2	147.500
L-Asparagine monohydrate	5794-13-8	7.500
L-Aspartic acid	56-84-8	6.650
L-Cysteine dihydrochloride	7048-04-6	31.290
L-Cystine hydrochloride monohydrate		17.560
L-Glutamic acid	56-86-0	7.350
L-Glutamine	56-85-9	365.000
L-Histidine hydrochloride monohydrate	5934-29-2	31.480
L-Isoleucine	73-32-5	54.470
L-Leucine	61-90-5	59.050
L-Lysine hydrochloride	657-27-2	91.250
L-Methionine	63-68-3	17.240
L-Phenylalanine	63-91-2	35.480
L-Proline	147-85-3	17.250
L-Serine	56-45-1	26.250
L-Threonine	72-19-5	53.450
L-Tryptophan	73-22-3	9.020
L-Tyrosine disodium salt	69847-45-6	48.100
L-Valine	72-18-4	52.850

Component	CAS Number	mg/L
VITAMINS
Choline chloride	67-48-1	8.980
D-Biotin	58-85-5	0.0035
D-Ca-Pantothenate	137-08-6	2.240
Folic acid	59-30-3	2.660
Nicotinamide	98-92-0	2.020
Pyridoxal hydrochloride	65-22-5	2.000
Pyridoxine hydrochloride	58-56-0	0.031
Riboflavin	83-88-5	0.219
Thiamine hydrochloride	67-03-8	2.170
Vitamin B12	68-19-9	0.680
OTHERS
D-Glucose	50-99-7	3151.000
DL-Thioctic acid	1077-28-7	0.105
HEPES buffer	7365-45-9	3574.500
Hypoxanthine sodium salt		2.400
Linoleic acid	60-33-3	0.042
myo-Inositol	87-89-8	12.600
Phenol red sodium salt	34487-61-1	8.630
Putrescine hydrochloride	333-93-7	0.081
Sodium pyruvate	113-24-6	110.000
Thymidine	50-89-5	0.365

Customization: pH, glucose, salt balance, HEPES, and full nutrient profile available on request. Contact support@diagnocine.com.

Quality Assurance

ISO 13485:2016 manufacturing & compliance

Manufactured under ISO 13485:2016 QMS with final packaging, testing, and customization at Diagnocine Precision in Totowa, New Jersey, USA.

verified

ISO 13485:2016 QMS

Full quality management system certification covering manufacturing, testing, and release for every production lot.

water_drop

Ultrapure Type 1 Water

All media prepared with 18.2 MΩ·cm resistivity water to ASTM D1193 / ISO 3696 standards.

biotech

ISO Class 5 Fill & Finish

Aseptic filling in validated ISO Class 5 laminar-flow workstations; 21 CFR Part 820 (QMSR) aligned.

assignment

Micro-Batch Precision

Small-batch manufacturing supports lot-to-lot nutrient consistency for reproducible perfusion studies.

Batch-level quality control. Endotoxin is controlled per manufacturing batch rather than per unit. Every batch is tested before release and must meet the release specification:

Endotoxin — LAL assay, USP <85> Bacterial Endotoxins Test; assay sensitivity 0.005 EU/mL; release specification < 0.05 EU/mL
pH, osmolality, conductivity, appearance and clarity
Sterility

A Certificate of Analysis is available on request.

Endotoxin — USP <85> BET

LAL assay per batch. Release specification: < 0.05 EU/mL.

Particulate — USP <788> Method 1

Light obscuration particle count confirms ≥10 µm and ≥25 µm compliance per lot.

Osmolality — USP <785>

Freezing-point osmometry per USP <785>. Contact support@diagnocine.com for lot-specific values.

Documentation — CoA & Full Lot Records

Certificate of Analysis with full QC panel, traceability, and release signatures for every lot.

Certificate of Analysis: Request via support@diagnocine.com with your lot number.

Product Comparison

How DCP-DM12H-T1X (FluxMPS™) compares

Side-by-side comparison against conventional 0.22 µm-filtered alternatives of the same base formulation.

Parameter	DCP-DM12H-T1X (FluxMPS™)	Conventional DMEM/F-12 (0.22 µm)	Standard DMEM/F-12 alternative
Grade	Microfluidics Suitable	Not specified	Not specified
Base Formulation	DMEM/F-12 (1:1) with 15mM HEPES	DMEM/F-12 Standard	DMEM/F-12 Equivalent
Final filtration pore size	0.04 µm	0.22 µm	0.22 µm
Number of filtration stages	4 stages	1 stage	1–2 stages
Mycoplasma-retentive filtration	check_circle	cancel	cancel
Endotoxin (release specification)	FluxMPS™ — < 0.05 EU/mL	Corning classical liquid media — < 0.25 EU/mL	Sigma-Aldrich DMEM complete medium — ≤ 2 EU/mL Gibco classical DMEM — Not specified (recorded per lot)
USP particulate compliance	check_circle USP <788> Method 1	cancel	cancel
Water quality	Ultrapure Type 1 (18.2 MΩ)	Purified water	Purified water
Manufacturing QMS	ISO 13485:2016	Variable	Variable
Microfluidic channel compatibility	check_circle Validated	cancel Risk of clogging	cancel Risk of clogging
Custom formulation	check_circle On request	cancel	Limited

Comparison figures from published supplier specifications, accessed 2026-09-02. Suppliers that publish no numeric endotoxin specification are shown as "Not specified".

FAQ

Frequently asked questions

Common questions about FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid.

Is DCP-DM12H-T1X suitable for organ-on-a-chip (OoC) applications?expand_more

Yes. DCP-DM12H-T1X uses our Quadruple-stage filtration (0.1 µm ×2 + 0.04 µm ×2), delivering low particulate counts that support microchannel integrity in OoC and MPS devices.

What makes the filtration process superior to standard 0.22 µm filtered media?expand_more

Standard 0.22 µm filtration leaves intact mycoplasma-sized particles (0.2–0.3 µm) and subvisible particulates. FluxMPS™ uses four sequential stages reaching 0.04 µm, delivering approximately 5× lower particulate counts by USP <788> Method 1.

What is the glucose concentration in DCP-DM12H-T1X, and how does the 15 mM HEPES affect culture conditions?expand_more

This formulation contains 3151 mg/L (3.151 g/L) glucose, plus 365 mg/L L-glutamine and 110 mg/L sodium pyruvate. The added 15 mM HEPES supplements the existing 1200 mg/L sodium bicarbonate buffer, providing extra buffering stability during handling outside a CO₂ incubator. Contact support@diagnocine.com for a custom concentration.

Does DCP-DM12H-T1X require a CO₂ incubator?expand_more

This formulation is HEPES-buffered in addition to its bicarbonate content, reducing CO₂ dependence. Standard CO₂ incubation remains compatible; validate the exact CO₂ level for your specific cell line and vessel geometry.

Can DCP-DM12H-T1X be supplemented with serum, growth factors, or other components?expand_more

Yes. FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid can be supplemented with FBS (5–20%), growth factors, antibiotics, or other additives per standard practice. When adding serum or other protein-containing supplements, filter through a 0.2 µm low-protein-binding PES or PVDF membrane (never 0.04 µm, which strips serum of essential lipoproteins and clogs quickly). Add supplements immediately before use.

What endotoxin level should I expect, and how is it verified?expand_more

Endotoxin is controlled per manufacturing batch, not per unit. Every batch is tested by LAL assay per USP <85> BET (assay sensitivity 0.005 EU/mL) and must meet the release specification of < 0.05 EU/mL before shipment. A Certificate of Analysis with the batch result is available from support@diagnocine.com.

Is a Certificate of Analysis (CoA) available, and what does it contain?expand_more

Yes. A batch-specific CoA is available for every shipment and includes: appearance, pH (USP <791>), endotoxin (USP <85> BET), sterility (USP <71>), particulate matter (USP <788> Method 1), raw material traceability, manufacturing date, lot number, expiry, and authorized release signatures. Request via support@diagnocine.com.

Scientific References

Supporting literature

Peer-reviewed publications supporting ultra-filtered media and microfluidic cell culture applications.

Huh D et al. (2010). Reconstituting organ-level lung functions on a chip. Science, 328(5986), 1662–1668. doi:10.1126/science.1188302
Bhatia SN & Ingber DE (2014). Microfluidic organs-on-chips. Nature Biotechnology, 32(8), 760–772. doi:10.1038/nbt.2989
Eagle H (1959). Amino acid metabolism in mammalian cell cultures. Science, 130(3373), 432–437. doi:10.1126/science.130.3373.432
Bhattacharya S et al. (2018). Challenges in maintaining cell viability during microfluidic experiments. Electrophoresis, 39(7), 997–1006. doi:10.1002/elps.201700375
Zhang YS et al. (2017). Multisensor-integrated organs-on-chips platform for automated in situ monitoring. PNAS, 114(12), E2293–E2302. doi:10.1073/pnas.1612906114
Vernetti L et al. (2017). Functional coupling of human microphysiology systems. Scientific Reports, 7, 42296. doi:10.1038/srep42296
Esch EW et al. (2015). Organs-on-chips at the frontiers of drug discovery. Nature Reviews Drug Discovery, 14(4), 248–260. doi:10.1038/nrd4539
Zheng F et al. (2021). Organ-on-a-chip systems: microengineering to biomimic living systems. Small, 17(7), 2004175. doi:10.1002/smll.202004175

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid

FluxMPS™ Dulbecco’s Modified Eagle Medium/ Ham's F-12 Nutrient Mixture (DMEM/F-12) (1:1) with 15mM HEPES: 1X Liquid

Engineered where standard media fails

Microchannel-safe purity

Total metabolic control

Ultrapure-grade water

Low background for imaging

Rich, stable nutrient profile

Customization on demand

Quadruple-stage filtration system

0.1 µm Prefiltration I

0.04 µm Final filtration I

0.1 µm Prefiltration II

0.04 µm Final filtration II — Polish

Performance vs. conventional media

Designed for next-generation cell culture platforms

Automated Bioreactors & Robotics

Micro Physiological System (MPS) & Chip

Warburg Effect & Metabolic Research

iPSC-Derived Models

Endothelial & Primary Cells

Metabolic Flux Analysis

Microscopy & Optical Sensing

Lot-release quality parameters

Full composition (mg/L)

ISO 13485:2016 manufacturing & compliance

ISO 13485:2016 QMS

Ultrapure Type 1 Water

ISO Class 5 Fill & Finish

Micro-Batch Precision

Endotoxin — USP <85> BET

Particulate — USP <788> Method 1

Osmolality — USP <785>

Documentation — CoA & Full Lot Records

How DCP-DM12H-T1X (FluxMPS™) compares

Frequently asked questions

Supporting literature

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