Anti-Osteoprotegerin Rabbit Polyclonal Antibody
Product#: SB-GB113749
$779.20
Availability:
Ships in 1-2 Weeks
Anti-Osteoprotegerin Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113749 |
| Size | ：100 uL |
| Protein full name | ：Tumor necrosis factor receptor superfamily member 11B |
| Synonym | ：Osteoclastogenesis inhibitory factor, Osteoprotegerin, Tnfrsf11b, Ocif, Opg, PDB5, TR1 |
| Immunogen | ：Recombinant protein corresponding to Mouse Osteoprotegerin |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：46 kDa |
| Observed MW. | ：46 kDa |
| Uniprot ID | ：O00300, O08712, O08727 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 |
heart, liver, lung, kidney, stomach |
Description
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
 |
Western blot analysis of OPG (GB113749) at dilution of 1: 1000 |
Aliases for OPG Gene
