Anti-MYL1 Rabbit Polyclonal Antibody

Product#: SB-GB112474

$560.00

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Anti-MYL1 Rabbit Polyclonal Antibody

General information

Cat. No.	：SB-GB112474
Size	：100 uL
Protein full name	：Myosin light chain 1/3, skeletal muscle isoform
Synonym	：MLC1/MLC3, MLC1F/MLC3F, Myosin light chain alkali 1/2, Myosin light chain A1/A2, Myl1, Mylf,
Immunogen	：Recombinant protein corresponding to Mouse Myl1
Isotype	：IgG
Purity	：Affinity purification
Subcellular location	：Cytoskeleton
Predicted MW.	：21 kDa
Observed MW.	：21 kDa
Uniprot ID	：P05977, P02600
Long Term Storage	：-20 ℃ or below
Shipping Condition	：Dry Ice
Storage Buffer	：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.

Application

Description

Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.

	Western blot analysis of Myl1 (GB112474) at dilution of 1: 4000 Lane 1: Mouse skeletal muscle tissue lysate Lane 2: Mouse skeletal muscle tissue lysate Lane 3: Mouse skeletal muscle tissue lysate
	Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000
	Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000
	Immunofluorescent analysis of paraformaldehyde-fixed mouse skeletal muscle using Myl1 (GB112474) at dilution of 1: 1000

Antigen Characterization

Human Diseases

Cardiovascular Diseases: Associated with cardiac muscle function and heart conditions.
Skeletal Muscle Disorders: Implications in muscle contraction abnormalities.
Hypertension: Linked to signaling pathways affecting vascular smooth muscle contraction

Cellular Signaling Pathways

Calcium Signaling: MYL1 is involved in calcium-induced contraction mechanisms in muscle cells.
RhoA Pathway: Plays a role in actin-myosin interaction during smooth muscle contraction.
Angiotensin II Signaling: Influences vasoconstriction through myosin light chain phosphorylation

References

Database, Rat Genome. MYL1 (Myosin, Light Chain 1) - Rat Genome Database, rgd.mcw.edu/rgdweb/report/gene/main.html?id=1598796.
Tissue Expression of Myl1 - Summary - The Human Protein Atlas, Human Protein Atlas, www.proteinatlas.org/ENSG00000168530-MYL1/tissue.
MYL1 Myosin Light Chain 1 [Homo Sapiens (Human)] - Gene - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Db=gene&Term=4632.
MYL1 Myosin, Light Polypeptide 1 [Mus Musculus (House Mouse)] - Gene - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, www.ncbi.nlm.nih.gov/gene?Cmd=DetailsSearch&Db=gene&Term=17901.
MYL1 Polyclonal Antibody.” Elabscience, www.elabscience.com/p-myl1_polyclonal_antibody-271442.html.

Aliases for MYL1 Gene