:Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer
:PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Application
Applications
Species
Dilution
Positive Tissue
IHC
Mouse, Rat
1: 3000-1: 6000
kidney, spleen, striatum
Description
Anion exchanger 1 (AE1), also known as band 3, is a 95-100 kDa transmembrane glycoprotein which is abundantly expressed in erythrocyte plasma membrane and mediates the electroneutral exchange of Cl- and HCO3-. It contains a 52-55 kDa C-terminal membrane crossing domain and a 43 kDa N-terminal cytoplasmic domain. Degradation of band 3 protein occurred during erythrocyte aging. The oxidative stress can also activate the proteolysis of band 3 through caspases.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using AE1 (GB113603) at dilution of 1: 6000
Immunohistochemistry analysis of paraffin-embedded rat kidney using AE1 (GB113603) at dilution of 1: 6000
Immunohistochemistry analysis of paraffin-embedded mouse spleen using AE1 (GB113603) at dilution of 1: 6000
Immunohistochemistry analysis of paraffin-embedded rat spleen using AE1 (GB113603) at dilution of 1: 6000
Immunohistochemistry analysis of paraffin-embedded mouse striatum using AE1 (GB113603) at dilution of 1: 6000