Anti-CDK5RAP1 Rabbit Polyclonal Antibody
Anti-CDK5RAP1 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113634 |
| Size | ：100 uL |
| Protein full name | ：Mitochondrial tRNA methylthiotransferase CDK5RAP1 |
| Synonym | ：C20orf34, C42, CDK5RAP1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, CDK5 activator-binding protein C42, CDK5 regulatory subunit-associated protein 1, RP5-1187J4.1 |
| Immunogen | ：Recombinant protein corresponding to Mouse CDK5RAP1 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：66 kDa |
| Observed MW. | ：72 kDa |
| Uniprot ID | ：Q96SZ6, Q9JLH6 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Rat | 1: 500-1: 800 |
HeLa, C6, A549 |
Description
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP1 contains one TRAM domain, which is thought to bind tRNA and deliver the RNA-modifying enzymatic domain to its target. There are 4 named isoforms of CDK5RAP1 that are produced as a result of alternative splicing events and are expressed at high levels in heart and skeletal muscle.
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Western blot analysis of CDK5RAP1 (GB113634) at dilution of 1: 800 |
Aliases for CDK5RAP1 Gene
- GeneCards Symbol: CDK5RAP1 2
- CDK5 Regulatory Subunit Associated Protein 1 2 3 5
- C20orf34 3 4 5
- HSPC167 2 3 5
- CGI-05 2 3 5
- C42 2 3 5
- Mt-TRNA-N6-(Dimethylallyl)Adenosine(37) Methylthiotransferase 3 4
- Mt-TRNA-2-Methylthio-N6-Dimethylallyladenosine Synthase 3 4
- Mitochondrial TRNA Methylthiotransferase CDK5RAP1 3 4
- CDK5 Activator-Binding Protein C42 3 4
- CDK5 Regulatory Subunit-Associated Protein 1 4
- Chromosome 20 Open Reading Frame 34 2
- EC 2.8.4.3 4
