Anti-CoREST Rabbit Polyclonal Antibody
Product#: SB-GB113633
$779.20
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Anti-CoREST Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113633 |
| Size | ：100 uL |
| Protein full name | ：REST corepressor 1 |
| Synonym | ：COREST, KIAA0071, Protein CoREST, RCOR, RCOR1, RCOR1Specific, Protein CoREST |
| Immunogen | ：Recombinant protein corresponding to Mouse CoREST |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：53 kDa |
| Observed MW. | ：53 kDa |
| Uniprot ID | ：Q9UKL0, Q8CFE3 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000-1: 2000 |
testis, brain, lung |
Description
RCOR1, also named as REST corepressor 1, is a 485 amino acid protein, which belongs to the CoREST family. RCOR1 is a essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. The calculated molecular weight of RCOR1 is a 53 kDa, but the phosphorylated RCOR1 is about 60-65 kDa.
 |
Western blot analysis of CoREST (GB113633) at dilution of 1: 2000 |
Aliases for CoREST Gene
