Anti-CoREST Rabbit Polyclonal Antibody
General information
| Cat. No. | :SB-GB113633 |
| Size | :100 uL |
| Protein full name | :REST corepressor 1 |
| Synonym | :COREST, KIAA0071, Protein CoREST, RCOR, RCOR1, RCOR1Specific, Protein CoREST |
| Immunogen | :Recombinant protein corresponding to Mouse CoREST |
| Isotype | :IgG |
| Purity | :Affinity purification |
| Predicted MW. | :53 kDa |
| Observed MW. | :53 kDa |
| Uniprot ID | :Q9UKL0, Q8CFE3 |
| Storage | :Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | :PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000-1: 2000 |
testis, brain, lung |
Description
RCOR1, also named as REST corepressor 1, is a 485 amino acid protein, which belongs to the CoREST family. RCOR1 is a essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. The calculated molecular weight of RCOR1 is a 53 kDa, but the phosphorylated RCOR1 is about 60-65 kDa.
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Western blot analysis of CoREST (GB113633) at dilution of 1: 2000 |
Aliases for CoREST Gene
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