Anti-DNA Polymerase Beta Rabbit Polyclonal Antibody
Anti-DNA Polymerase Beta Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112436 |
| Size | ：100 uL |
| Protein full name | ：DNA polymerase beta |
| Synonym | ：POLB, DNA pol beta, DNA directed DNA polymerase beta |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse DNA Polymerase beta |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Cytoplasm, Nucleus |
| Uniprot ID | ：Q8K409, P06766 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| IHC | Mouse, Rat | 1: 2000-1: 4000 | liver, testis, ovary, brain, spleen, lung, prefrontal lobe, kidney |
| IF | Mouse, Rat | 1: 500-1: 1000 | ovary, brain, kidney |
Description
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
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Immunohistochemistry analysis of paraffin-embedded mouse liver using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded mouse testis using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded mouse ovary using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded mouse spleen using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded rat lung using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded rat prefrontal lobe using POLB (GB112436) at dilution of 1: 4000 |
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Immunohistochemistry analysis of paraffin-embedded rat kidney using POLB (GB112436) at dilution of 1: 4000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse ovary using POLB (GB112436) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using POLB (GB112436) at dilution of 1: 1000 |
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Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using POLB (GB112436) at dilution of 1: 1000 |
Aliases for POLB Gene
- GeneCards Symbol: POLB 2
- DNA Polymerase Beta 2 3 4 5
- Polymerase (DNA Directed), Beta 2 3
- Polymerase (DNA) Beta 2 3
- DNA Polymerase Beta Subunit 3
- DNA Pol Beta 3
- EC 4.2.99.- 4
- EC 2.7.7.7 4
