Anti Human PR common mouse monoclonal antibody (A9621A)
PR common: Progesterone Receptor
General information
| Cat. No. |
:FNK-PP-A9621A-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human/ Rat |
| Purification |
:Ammonium sulfate fractionation. |
| Clone No |
:A9621A |
| Lot. |
:A-1 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Nomenclature |
:NR3C3 |
| Application |
:ELISA : 10 ng/mL (A492=1.0)
:Western Blot : 1 ug/mL
:Non reducing Western Blot: 1 ug/mL
:Immunohistochemistry: 10-20 ug/mL |
| Specificity |
:This antibody specifically recognizes human PR isoform A and B, and cross reacts with mouse and rat
PR isoform A and B |
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative |
| Genbank |
:M15716 |
Description
Progesterone receptor (PR; NR3C3) is a member of steroid receptor (GR, AR, MR, ER). PR binds progesterone. PR is expressed in uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast, and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively.

Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human PR isoform A (166-263 aa) .
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for PGR Gene
- Progesterone Receptor 2 3 4 5
- NR3C3 2 3 4
- PR 2 3 4
- Nuclear Receptor Subfamily 3 Group C Member 3 3 4
- PGR 5