Anti-Rpn5 (S.cerevisiae) antibody, affinity purified
DiagnoCine offers excellent RPN (5, 7, 9, 12) | Affinity Purified Antibodies from S.cerevisiae to researchers studying Ubiquitination, Proteosome, DNA repair, Signal transduction, Apoptosis, Metabolic Regulation, Damaged & Misfolded Proteins, and Cell Cycle Regulation.
Human diseases include Neurodegenerative Diseases, Cardiovascular Diseases, Inflammatory Responses, Autoimmune Diseases, Systemic DNA Damage responses leading to Alzheimer's Disease, Parkinson's Disease, Pick's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Creutzfeldt–Jakob Disease, Muscular Dystrophies, and Several Rare forms of Neurodegenerative Diseases associated with Dementia.
RPN antibodies have excellent quality and this highly pure antibody can be adapted for Western blotting, Immunoprecipitation, and other methods after optimization.
General Information
Cat. No. | :FNK-62-203 |
Size | :100µl |
Host Animal | :Rabbit |
Reactivity | :S.cerevisiae Rpn5p. Not tested with other species |
Label | :Unlabeled |
Product | :Rabbit polyclonal antibody affinity purified with recombinant Rpn5p |
Immunogen | :Recombinant yeast Rpn5p expressed in E. coli |
Application |
|
Storage | :-20℃. To avoid repeated freezing and thawing, store the antibody in aliquots |
Form | :Purified IgG in 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide |
Data Link | :SGD RPN5/YDL147W |
Description
The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short-lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation (1). Rpn5p is an essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7 (2, 3,). It consists of 445 amino acids with a molecular weight of 51,768.
Fig.1 Detection of Rpn5 (52kDa) in the crude extract of S. cerevisiae by Western blotting using this antibody |
References
Aliases for PSMD12 Gene