Anti Human NGFI-B alpha mouse monoclonal antibody (H1648)

Product#: PP-H1648-00
$577.00
Availability:
Ships in 1-2 weeks

Anti Human NGFI-B alpha mouse monoclonal antibody (H1648)
NGFI-B alpha: Nerve growth factor-induced clone B alpha


General information 

Cat. No. :PP-H1648-00
Size 100 ul
Antigen Species Human    
Host Species Mouse
Cross Reactivity :Human
Purification Ammonium sulfate fractionation.
Clone No :H1648
Lot. A-1
Concentration 1 mg/mL
Ig Class G2a
Nomenclature NR4A1
Application   ELISA : 0.3 ug/mL
Western Blot : 1 ug/mL
:Immunoprecipitation : Decide by use
Specificity This antibody specifically recognizes human NGFI-B alpha but does not recognize human NGFI-B beta
    and gamma. Not yet tested in other species.
Storage Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
    Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.
Form Physiological saline with 0.1% NaN3 as a preservative
Genbank L13740


Description


Nerve growth factor inducible factor I-B alpha (NGFI-Ba, NAK1, TR3; NR4A1) is a member of orphan nuclear receptor. NGFI-Ba is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate. Its expression is induced in response to various stress stimuli and growth factors. NGFI-Ba is involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis. RXR has been shown to be a partner for NR4A1.


Origin

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human NGFI-B alpha (2-249 aa) .

Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
 

Reference 

  1. Takezawa S, et al. The EMBO Journal 26, 764-774, 2007



Aliases for NR4A1 Gene

  • Nuclear Receptor Subfamily 4 Group A Member 1 2 3 4 5
  • Nuclear Hormone Receptor NUR/77 3 4
  • Early Response Protein NAK1 3 4
  • Orphan Nuclear Receptor HMR 3 4
  • Orphan Nuclear Receptor TR3 3 4
  • Testicular Receptor 3 3 4
  • GFRP1 3 4
  • NAK-1 2 3
  • NGFIB 2 3
  • NUR77 2 3
  • ST-59 3 4
  • HMR 3 4
  • N10 2 3
  • TR3 2 3
  • Nerve Growth Factor IB Nuclear Receptor Variant 1 3
  • Nuclear Receptor Subfamily 4, Group A, Member 1 2
  • Growth Factor-Inducible Nuclear Protein N10 3
  • Steroid Receptor TR3 3
  • TR3 Orphan Receptor 3
  • Hormone Receptor 3
  • NR4A1 5
  • Nur77 4
  • NP10 3
  • NAK1 4

Logo_ppmx.gif

Satisfaction
Quality Rating
Value Rating
Style Rating
X