Anti Human NGFI-B alpha mouse monoclonal antibody (H1648)
Product#: FNK-PP-H1648-00
$501.52
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Anti Human NGFI-B alpha mouse monoclonal antibody (H1648)
NGFI-B alpha: Nerve growth factor-induced clone B alpha
General information
| Cat. No. | ：FNK-PP-H1648-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H1648 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR4A1 |
| Application | ：ELISA : 0.3 ug/mL ：Western Blot : 1 ug/mL ：Immunoprecipitation : Decide by use |
| Specificity | ：This antibody specifically recognizes human NGFI-B alpha but does not recognize human NGFI-B beta and gamma. Not yet tested in other species. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：L13740 |
Description
Nerve growth factor inducible factor I-B alpha (NGFI-Ba, NAK1, TR3; NR4A1) is a member of orphan nuclear receptor. NGFI-Ba is expressed in brain, adrenal, thyroid, liver, testis, ovary, thymus, muscle, lung and prostate. Its expression is induced in response to various stress stimuli and growth factors. NGFI-Ba is involved in mediating apoptotic signaling in thymocytes and tumor cells, as well as having a role in signaling in the hypothalamic-pituitary axis. RXR has been shown to be a partner for NR4A1.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human NGFI-B alpha (2-249 aa) .
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Takezawa S, et al. The EMBO Journal 26, 764-774, 2007
Aliases for NR4A1 Gene
- Nuclear Receptor Subfamily 4 Group A Member 1 2 3 4 5
- Nuclear Hormone Receptor NUR/77 3 4
- Early Response Protein NAK1 3 4
- Orphan Nuclear Receptor HMR 3 4
- Orphan Nuclear Receptor TR3 3 4
- Testicular Receptor 3 3 4
- GFRP1 3 4
- NAK-1 2 3
- NGFIB 2 3
- NUR77 2 3
- ST-59 3 4
- HMR 3 4
- N10 2 3
- TR3 2 3
- Nerve Growth Factor IB Nuclear Receptor Variant 1 3
- Nuclear Receptor Subfamily 4, Group A, Member 1 2
- Growth Factor-Inducible Nuclear Protein N10 3
- Steroid Receptor TR3 3
- TR3 Orphan Receptor 3
- Hormone Receptor 3
- NR4A1 5
- Nur77 4
- NP10 3
- NAK1 4
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