Anti Human LGI-1 mouse monoclonal antibody
General information
| Cat. No. | :FNK-PP-Z0751-0C |
| Size | :100 ul |
| Antigen Species | :Human |
| Host Species | :Mouse |
| Cross Reactivity | :Human |
| Purification | :Affinity chromatography |
| Clone No | :Z0751 |
| Concentration | :1 mg/mL |
| Ig Class | :G2a |
| Application | :ELISA,Western Blot |
| Specificity |
:This antibody specifically recognizes human LGI-1 and cross reacts with mouse LGI-1.
Not yet tested in other species. |
| Storage | :Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | :Physiological saline with 0.1% NaN3 |
| Genbank | :AF055636 |
*LGI-1: Leucine-rich glioma-inactivated protein 1
Origin
Produced in culture supernatant from hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirusexpressed recombinant human LGI-1 (193-233 aa) .
LGI-1 is the protein predominantly expressed and secreted in neural tissues, ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Yokoi N, et al. Nat Med. 2015; 21(1): 19-26
Aliases for LGI1 Gene

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