Anti Human GR common mouse monoclonal antibody (H8004)

Product#: PP-H8004-00
$577.00
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Anti Human GR common mouse monoclonal antibody (H8004)
GR: Glucocorticoid Receptor


General information 

Cat. No. PP-H8004-00
Size 100 ul
Antigen Species Human    
Host Species Mouse
Cross Reactivity Human
Purification Ammonium sulfate fractionation.
Clone No H8004
Lot. A-1
Concentration 1 mg/mL
Ig Class G2a
Nomenclature NR3C1
Application   ELISA (0.35 ug/mL(A450=1.0)),Western Blot (1-10 ug/mL), Immunohistochemistry (10 ug/mL)
Specificity
This antibody specifically recognizes human GR alpha and beta and cross reacts with rat GR alpha
    and beta. Not yet tested in other species.
Storage Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
    Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.
Form Physiological saline with 0.1% NaN3 as a preservative
Genbank X03225


Description

Glucocorticoid receptor (GR; NR3C1) is a member of steroid receptor (AR, ER, MR, PR). GR is expressed in almost all human tissues and organs.GR binds to its sequences as an homodimer. Two different forms, GRa and GRb, differing in their C-terminal parts were isolated. GRa is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GRb does not bind glucocorticoids.
 
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Origin

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human GR alpha (2-60 aa).

Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
 


Aliases for NR3C1 Gene

  • Nuclear Receptor Subfamily 3 Group C Member 1 2 3 4 5
  • Glucocorticoid Receptor 2 3 4
  • GR 2 3 4
  • Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) 2 3
  • GRL 3 4
  • Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(54) 3
  • Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(77) 3
  • Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(93) 3
  • Nuclear Receptor Subfamily 3, Group C, Member 1 2
  • Glucocorticoid Nuclear Receptor Variant 1 3
  • GCRST 3
  • NR3C1 5
  • GCCR 3
  • GCR 3

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