Anti Human PPAR gamma 2 mouse monoclonal antibody (K8450B)

Product#: PP-K8450B-00
Ships in 1-2 weeks

Anti Human PPAR gamma 2 mouse monoclonal antibody (K8450B)
PPAR gamma: Peroxisome Proliferator-Activated Receptor gamma

General information 

Cat. No. :PP-K8450B-00
Size 100 ul
Antigen Species Human    
Host Species Mouse
Cross Reactivity :Human/ Mouse
Purification Ammonium sulfate fractionation.
Clone No :K8450B
Lot. A-2
Concentration 1 mg/mL
Ig Class G2a
Nomenclature NR1C3
Application   ELISA : 0.1 ug/mL
Western Blot : 2 ug/mL
Non reducing Western Blot 4 ug/mL
:Supershift Assay: 100 ug/mL
Specificity This antibody specifically recognizes human PPAR gamma2 and cross reacts with mouse PPAR gamma 2.
    This antibody does not recognize human PPAR gamma1, alpha and delta. Not yet tested in other species.
Storage Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
    Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.
Form Physiological saline with 0.1% NaN3 as a preservative
Genbank U79012


Peroxisome proliferator-activated receptor gamma (PPARg; NR1C3) is a member of orphan nuclear receptor. Oxidized metabolites of linoleic acid, 9- hydroxyctadienoic acid (9-HODE) and 13-HODE are activators and ligands of PPARg. PPARg is expressed in white adipose tissue, intestinal mucosa, colon, spleen, monocytes, macrophages, retina, cartilage, osteoclast and skeletal muscle. PPARg plays important roles in lipid and glucose metabolism, and have been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members were called PPARa, b, g. Three N-terminal isoforms, called g1, g2 and g3, are known to arise by alternative splicing and promoter usage from the PPARg gene. RXR is an obligate partner for PPAR.


Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human PPAR gamma2 (2-28 aa).

Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.


  1. Tanaka T, et al . J Atheroscler Thromb, 9(5): 233-241, 2002.

Aliases for PPARG Gene

  • Peroxisome Proliferator Activated Receptor Gamma 2 3 5
  • Peroxisome Proliferator-Activated Receptor Gamma 2 3 4
  • NR1C3 2 3 4
  • Nuclear Receptor Subfamily 1 Group C Member 3 3 4
  • PPAR-Gamma 3 4
  • PPARgamma 2 3
  • PPARG1 2 3
  • PPARG2 2 3
  • Peroxisome Proliferator-Activated Nuclear Receptor Gamma Variant 1 3
  • Peroxisome Proliferator-Activated Receptor-Gamma Splicing 3
  • Peroxisome Proliferative Activated Receptor, Gamma 2
  • Peroxisome Proliferator-Activated Receptor-Gamma 5 3
  • PPARG5 3
  • CIMT1 3
  • PPARG 5
  • GLM1 3


Quality Rating
Value Rating
Style Rating