Anti-Cytochrome B5 Rabbit Polyclonal Antibody

Product#: SB-GB112409
$560.00
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Anti-Cytochrome B5 Rabbit Polyclonal Antibody 

 

General information 

Cat. No. SB-GB112409
Size :100 uL
Protein full name Cytochrome b5
Synonym Cyb5a, Cyb5, CYB5A, MCB5 , Microsomal cytochrome b5 type A, Type 1 cyt b5
Immunogen Recombinant protein corresponding to Mouse Cytochrome b5
Isotype IgG
Purity Affinity purification
Predicted MW. 15 kDa
Observed MW. 17 kDa
Uniprot ID P56395P00173
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Shipping Condition  :Dry Ice 
Storage Buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.


Application
 
Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 250-1: 500 liver


Description


Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.

 
GB112409-2.png

Western blot analysis of Cytochrome b5 (GB112409) at dilution of 1: 500

Lane 1: Mouse liver tissue lysate

Lane 2: Rat liver tissue lysate

 
 
Human Diseases
  • Leber's Hereditary Optic Neuropathy: Associated with mutations in cytochrome b5, leading to vision loss.
  • Myopathy: Mutations can cause muscle weakness and related disorders 2.

Cellular Signaling Pathways
  • Involved in the electron transport chain, facilitating electron transfer to various enzymes.
  • Plays a role in fatty acid desaturation and elongation processes.
  • Impacts metabolic pathways related to drug metabolism and detoxification 23.

Aliases for CYB5 Gene
  • GeneCards Symbol: CYB5A 2 
  • Cytochrome B5 Type A 2 3 5
  • CYB5 3 4 5
  • Cytochrome B5 Type A (Microsomal) 2 3
  • Cytochrome B5 3 4
  • MCB5 3 4
  • Epididymis Secretory Sperm Binding Protein 3
  • Microsomal Cytochrome B5 Type A 4
  • Cytochrome B5 (Microsomal) 2
  • Cytochrome B-5 2
  • Type 1 Cyt-B5 3
  • METAG 3

References 
  • 12365-1-AP.” Cytochrome B5 Antibody (12365-1-AP) | Proteintech, 31 Aug. 2024, www.ptglab.com/products/CYB5A-Antibody-12365-1-AP.htm. 
  • Cytochrome B5 Polyclonal Antibody.” Cytochrome B5 Polyclonal Antibody (PA5-63584), www.thermofisher.com/antibody/product/Cytochrome-B5-Antibody-Polyclonal/PA5-63584. 
  • Anti-Cytochrome B5 Antibody.” Abcam, www.abcam.com/en-us/products/primary-antibodies/cytochrome-b5-antibody-ab69801. 
  • Cytochrome B5 Antibody (ABIN6283030).” Cytochrome B5 Antibody (ABIN6283030), www.antibodies-online.com/antibody/3184220/anti-Cytochrome+b5+CYTB5+Internal+Region+antibody/?sku=6283030. 
  • Z;, Lan F;Tang Y;Huang C;Zhu. “Determination of Concentration of Cytosolic NADH-Cytochrome B5 Reductase in Erythrocytes from Normal Chinese Adults, Neonates and Patients with Hereditary Methemoglobinemia by Double-Antibody Sandwich Elisa.” Acta Haematologica, U.S. National Library of Medicine, pubmed.ncbi.nlm.nih.gov/9691146/. 
 

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