Anti-beta Actin Rabbit Polyclonal Antibody

Product#: SB-GB11001
$779.20
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Anti-beta Actin Rabbit Polyclonal Antibody

 

General information 

Cat. No. SB-GB11001
Size :100 uL
Protein full name Actin, cytoplasmic 1
Synonym ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin beta, Beta Cytoskeletal Actin  
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse β-Actin
Isotype IgG
Predicted MW. 42 kDa
Observed MW. 45 kDa
Purity Affinity purification
Uniprot ID P60709, P60710, P60711
Application   WB
Species Human, Rat, Mouse
Dilution 1:2000
Positive tissue lung, kidney, brain
Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.


Description

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility .
 

Western blot analysis of β-Actin (GB11001) at dilution of 1:2000.

Lane 1:U251 cell lysate

Lane 2:N2A cell lysate

Lane 3:C6 cell lysate

Lane 4:Mouse lung tissue lysate

Lane 5:Mouse kidney tissue lysate

Lane 6:Mouse brain tissue lysate

Lane 7:Rat lung tissue lysate

Lane 8:Rat kidney tissue lysate

Lane 9:Rat brain tissue lysate

 
 

References
 
  1. Chen, M.-L. et al Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.Theranostics 11,2395-2409(2021).PMID 33500732 Application: WB IF 11.556
  2. Shi, Y. et al Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.Gut microbes 13,1946369-1946369(2021).PMID 34275417 Application: WB IF 10.245
  3. Ma, X. et al Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder. Journal of neuroinflammation 18,201-201(2021).PMID 34526069 Application: WB IF 8.322
  4. Yuan, C. et al miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5.Cancer cell international 21,390-390(2021).PMID 34289837 Application: WB IF 5.722
  5. Chen, H. et al Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complications.Journal of cellular and molecular medicine 25,4363-4372(2021).PMID 33811439 Application: WB IF 5.31
  6. Hua, R. et al Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway.Journal of Cell Science 133,jcs248898(2020).PMID 33097608 Application: WB IF 5.285
  7. Wang, X., Wang, F., Zhang, Z.-G., Yang, X.-M. & Zhang, RSTK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8(+) T-Cells.Journal of immunology research 2020,7263602-7263602(2020).PMID 33062724 Application: WB IF 4.818
  8. Pi, X.-J. et al Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.Pharmaceutical biology 59,1117-1125(2021).PMID 34403300 Application: WB IF 3.503
  9. Jiang, F. et al Fluorofenidone attenuates paraquat?induced pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling pathway and autophagy.Molecular medicine reports 23,405(2021).PMID 33786626 Application: WB IF 2.952
  10. Liu, C. et al Serum?derived exosomes from house dust mite?sensitized guinea pigs contribute to inflammation in BEAS-2B cells via the TLR4-NF-κB pathway.Molecular medicine reports 24,747(2021).PMID 34458929 Application: WB IF 2.952


Aliases for beta ACTB Gene

  • Actin Beta 2 3 5
  • Actin, Cytoplasmic 1 3 4
  • PS1TP5-Binding Protein 1 3
  • Beta Cytoskeletal Actin 3
  • I(2)-Actin 3
  • Beta-Actin 4
  • PS1TP5BP1 3
  • Β-Actin 2
  • BRWS1 3

 
 

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