Anti-beta Actin Rabbit Polyclonal Antibody
General information
| Cat. No. | :SB-GB11001 |
| Size | :100 uL |
| Protein full name | :Actin, cytoplasmic 1 |
| Synonym | :ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin beta, Beta Cytoskeletal Actin |
| Immunogen | :KLH conjugated Synthetic peptide corresponding to Mouse β-Actin |
| Isotype | :IgG |
| Predicted MW. | :42 kDa |
| Observed MW. | :45 kDa |
| Purity | :Affinity purification |
| Uniprot ID | :P60709, P60710, P60711 |
| Application | :WB |
| Species | :Human, Rat, Mouse |
| Dilution | :1:2000 |
| Positive tissue | :lung, kidney, brain |
| Storage | :Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | :PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Description
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility .
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Western blot analysis of β-Actin (GB11001) at dilution of 1:2000. Lane 1:U251 cell lysate Lane 2:N2A cell lysate Lane 3:C6 cell lysate Lane 4:Mouse lung tissue lysate Lane 5:Mouse kidney tissue lysate Lane 6:Mouse brain tissue lysate Lane 7:Rat lung tissue lysate Lane 8:Rat kidney tissue lysate Lane 9:Rat brain tissue lysate |
References
- Chen, M.-L. et al Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.Theranostics 11,2395-2409(2021).PMID 33500732 Application: WB IF 11.556
- Shi, Y. et al Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.Gut microbes 13,1946369-1946369(2021).PMID 34275417 Application: WB IF 10.245
- Ma, X. et al Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder. Journal of neuroinflammation 18,201-201(2021).PMID 34526069 Application: WB IF 8.322
- Yuan, C. et al miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5.Cancer cell international 21,390-390(2021).PMID 34289837 Application: WB IF 5.722
- Chen, H. et al Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complications.Journal of cellular and molecular medicine 25,4363-4372(2021).PMID 33811439 Application: WB IF 5.31
- Hua, R. et al Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway.Journal of Cell Science 133,jcs248898(2020).PMID 33097608 Application: WB IF 5.285
- Wang, X., Wang, F., Zhang, Z.-G., Yang, X.-M. & Zhang, RSTK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8(+) T-Cells.Journal of immunology research 2020,7263602-7263602(2020).PMID 33062724 Application: WB IF 4.818
- Pi, X.-J. et al Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.Pharmaceutical biology 59,1117-1125(2021).PMID 34403300 Application: WB IF 3.503
- Jiang, F. et al Fluorofenidone attenuates paraquat?induced pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling pathway and autophagy.Molecular medicine reports 23,405(2021).PMID 33786626 Application: WB IF 2.952
- Liu, C. et al Serum?derived exosomes from house dust mite?sensitized guinea pigs contribute to inflammation in BEAS-2B cells via the TLR4-NF-κB pathway.Molecular medicine reports 24,747(2021).PMID 34458929 Application: WB IF 2.952
Aliases for beta ACTB Gene
- Actin Beta 2 3 5
- Actin, Cytoplasmic 1 3 4
- PS1TP5-Binding Protein 1 3
- Beta Cytoskeletal Actin 3
- I(2)-Actin 3
- Beta-Actin 4
- PS1TP5BP1 3
- Β-Actin 2
- BRWS1 3










