Anti-alpha Sarcoglycan Rabbit Polyclonal Antibody
Product#: SB-GB113664
$779.20
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Anti-alpha Sarcoglycan Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB113664 |
| Size | ：100 uL |
| Protein full name | ：Alpha-sarcoglycan |
| Synonym | ：50-DAG, 50DAG, A2, adhalin, ADL, Alpha SG, DAG2, DMDA2, Dystroglycan 2, LGMD2D, SCARMD1, SGCA |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse alpha Sarcoglycan |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Cell membrane, Cytoplasm, Cytoskeleton |
| Predicted MW. | ：43 kDa |
| Observed MW. | ：55 kDa |
| Uniprot ID | ：Q16586, P82350 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 300-1: 600 |
heart, skeletal muscle |
| IHC | Mouse | 1: 300-1: 600 | skeletal muscle |
Description
Alpha-sarcoglycan is a member of the sarcoglycan-sarcospan complex (SG-SSPN), which is constituted by α/?-, β-, γ-, and δ-SGs as well as SSPN. Alpha-sarcoglycan gene expression is exclusive of striated muscle and is finely regulated during myogenic differentiation, where the amount of alpha-sarcoglycan transcript is selectively increased after differentiation to myotubes (MTs). Alpha sarcoglycan's disruption causes limb-girdle muscular dystrophy.
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Western blot analysis of SGCA (GB113664) at dilution of 1: 600 |
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Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using SGCA (GB113664) at dilution of 1: 600
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Aliases for SGCA Gene
- GeneCards Symbol: SGCA 2
- Sarcoglycan Alpha 2 3 5
- Adhalin 2 3 4 5
- SCARMD1 2 3 5
- LGMD2D 2 3 5
- DMDA2 2 3 5
- ADL 3 4 5
- Sarcoglycan, Alpha (50kDa Dystrophin-Associated Glycoprotein) 2 3
- 50 KDa Dystrophin-Associated Glycoprotein 3 4
- Limb Girdle Muscular Dystrophy 2D 2 3
- Alpha-Sarcoglycan 3 4
- Dystroglycan-2 3 4
- 50kD DAG 2 3
- Alpha-SG 3 4
- 50DAG 3 4
- DAG2 3 4
- A2 2 5
- LGMDR3 3