Anti Human RXR alpha mouse monoclonal antibody (K8508)
Product#: FNK-PP-K8508-00
$501.52
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Anti Human RXR alpha mouse monoclonal antibody (K8508)
RXR alpha: Retinoid X Receptor alpha
General information
| Cat. No. | ：FNK-PP-K8508-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：K8508 |
| Lot. | ：A-2 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR2B1 |
| Application | ：ELISA : 0.3 ug/mL ：Western Blot : 1 ug/mL ：Non reducing Western Blot : 3 ug/mL |
| Specificity |
：This antibody specifically recognizes human RXR alpha and cross reacts with mouse and rat RXR alpha.
This antibody does not recognize human RXR beta and gamma. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：X52773 |
Description
Retinoid X receptor alpha (RXRa; NR2B1) is a member of orphan nuclear receptor. 9-cis retinoic acid can bind to RXR. RXRa is expressed in liver, muscle, lung, kidney, intestine, heart and spleen. RXRa plays roles in a variety of processes including embryonic patterning and organogenesis, cell proliferation and differentiation. RXRs commonly function as heterodimers with other members of the nuclear receptor superfamily.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR alpha (2-133 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
References
- Jae Mi Suh, et al. Mol Endocrinol, Dec. 2006, 20(12): 3412-3420
- Jun Qin, et al. Developmemtal Dynamics, 2007, 236: 810-820
Aliases for RXRA Gene
