Anti Human RXR alpha mouse monoclonal antibody (K8508)

Product#: PP-K8508-00
$577.00
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Anti Human RXR alpha mouse monoclonal antibody (K8508)
RXR alpha: Retinoid X Receptor alpha


General information 

Cat. No. PP-K8508-00
Size 100 ul
Antigen Species Human    
Host Species Mouse
Cross Reactivity Human
Purification Ammonium sulfate fractionation.
Clone No K8508
Lot. A-2
Concentration 1 mg/mL
Ig Class G2a
Nomenclature NR2B1
Application   ELISA : 0.3 ug/mL
Western Blot : 1 ug/mL
Non reducing Western Blot : 3 ug/mL
Specificity
This antibody specifically recognizes human RXR alpha and cross reacts with mouse and rat RXR alpha.
    This antibody does not recognize human RXR beta and gamma.
Storage Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
    Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.
Form Physiological saline with 0.1% NaN3 as a preservative
Genbank X52773


Description


Retinoid X receptor alpha (RXRa; NR2B1) is a member of orphan nuclear receptor. 9-cis retinoic acid can bind to RXR. RXRa is expressed in liver, muscle, lung, kidney, intestine, heart and spleen. RXRa plays roles in a variety of processes including embryonic patterning and organogenesis, cell proliferation and differentiation. RXRs commonly function as heterodimers with other members of the nuclear receptor superfamily.
 

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Origin

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR alpha (2-133 aa).

Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
 

References

  1. Jae Mi Suh, et al. Mol Endocrinol, Dec. 2006, 20(12): 3412-3420
  2. Jun Qin, et al. Developmemtal Dynamics, 2007, 236: 810-820



Aliases for RXRA Gene

  • Retinoid X Receptor Alpha 2 3 4 5
  • Nuclear Receptor Subfamily 2 Group B Member 1 2 3 4
  • NR2B1 2 3 4
  • Retinoic Acid Receptor RXR-Alpha 3 4
  • Retinoid X Nuclear Receptor Alpha 3
  • Retinoid X Receptor, Alpha 2
  • RXRA 5

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