Anti Human ROR gamma mouse monoclonal antibody (H6437)

Product#: PP-H6437-00
$577.00
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Anti Human ROR gamma mouse monoclonal antibody (H6437)
ROR gamma: RAR-related orphan receptor gamma


General information 

Cat. No. PP-H6437-00
Size 100 ul
Antigen Species Human    
Host Species Mouse
Cross Reactivity Human
Purification Ammonium sulfate fractionation.
Clone No H6437
Lot. A-1
Concentration 1 mg/mL
Ig Class G2a
Nomenclature NR1F3
Application   ELISA : 0.3 ug/mL (A450=0.5)
Western Blot : 1 ug/mL
Specificity
This antibody specifically recognizes human ROR gamma but does not recognize ROR alpha and beta.
    Not yet tested in other species.
Storage Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
    Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.
Form Physiological saline with 0.1% NaN3 as a preservative
Genbank U16997


Description


Retinoic acid-related orphan receptor gamma (RORg, TOR, RORC; NR1F3) is a member of orphan nuclear receptor. RORg is expressed in muscle, thymus, testis, pancreas, prostate, heart and liver. RORg plays a role in thymocyte development and homeostasis. RORs bind to DNA as monomers on half-site elements with 5' A/T-rich extension. An N-terminal isoform of RORg, RORgt, has been shown to be specifically expressed in the thymus. 


Origin

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human ROR gamma (2-30 aa) .

Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
 
 

Aliases for RORC Gene

  • RAR Related Orphan Receptor C 2 3 5
  • NR1F3 2 3 4
  • RORG 2 3 4
  • RZRG 2 3 4
  • Nuclear Receptor Subfamily 1 Group F Member 3 3 4
  • RAR-Related Orphan Receptor C 2 4
  • Nuclear Receptor ROR-Gamma 3 4
  • Nuclear Receptor RZR-Gamma 3 4
  • TOR 2 3
  • RAR-Related Orphan Nuclear Receptor Variant 2 3
  • Retinoid-Related Orphan Receptor Gamma 3
  • Retinoid-Related Orphan Receptor-Gamma 4
  • Retinoic Acid-Binding Receptor Gamma 3
  • RZR-GAMMA 3
  • IMD42 3
  • RORC 5

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