Anti Human PPAR alpha mouse monoclonal antibody (H0723)
Anti Human PPAR alpha mouse monoclonal antibody (H0723)
PPAR alpha: Peroxisome Proliferator-Activated Receptor alpha
General information
| Cat. No. | ：FNK-PP-H0723-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human/ Mouse |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H0723 |
| Lot. | ：A-3 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR1C1 |
| Application | ：ELISA : 0.1 ug/mL ：Western Blot : 2 ug/mL ：Supershift Assay: 100 ug/mL |
| Specificity | ：This antibody specifically recognizes human PPAR alpha and cross reacts with mouse PPAR alpha. This antibody does not recognize human PPAR gamma and delta. Not yet tested in other species. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：U79012 |
Description
Peroxisome proliferator-activated receptor alpha (PPARa; NR1C1) is a member of orphan nuclear receptor. PPARa exhibit the highest affinity with unsaturated fatty acids, linolenic and linolenic acids. PPARa is expressed in brown fat, liver, kidney, heart, mucosa of the stomach and duodenum, retina, adrenal gland, skeletal muscle, pancreatic islets and smooth muscle cells. PPARa plays important roles in lipid and glucose metabolism, and have been implicated in obesity-related metabolic diseases such as hyperlipidemia, insulin resistance, and coronary artery disease. Three members were called PPARa, b, g. RXR is an obligate partner for PPAR.
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human PPAR alpha (4-96 aa) .
Note
Aliases for PPARA Gene
- Peroxisome Proliferator Activated Receptor Alpha 2 3 5
- Peroxisome Proliferator-Activated Receptor Alpha 2 3 4
- NR1C1 2 3 4
- Peroxisome Proliferative Activated Receptor, Alpha 2 3
- Nuclear Receptor Subfamily 1 Group C Member 1 3 4
- PPAR-Alpha 3 4
- HPPAR 2 3
- PPAR 3 4
- Peroxisome Proliferator-Activated Nuclear Receptor Alpha Variant 3 3
- PPARalpha 3
- PPARA 5
