Anti Human GR common mouse monoclonal antibody (H8031)
Product#: FNK-PP-H8031-00
$501.52
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Anti Human GR common mouse monoclonal antibody (H8031)
GR: Glucocorticoid Receptor
General information
| Cat. No. | ：FNK-PP-H8031-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H8031 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G2a |
| Nomenclature | ：NR3C1 |
| Application | ：ELISA (0.3 ug/mL),Western Blot (1 ug/mL), Immunohistochemistry (10 ug/mL) |
| Specificity |
：This antibody specifically recognizes human GR alpha and beta, and cross reacts with mouse and
rat GR alpha and beta. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：X03225 |
Description
Glucocorticoid receptor (GR; NR3C1) is a member of steroid receptor (AR, ER, MR, PR). GR is expressed in almost all human tissues and organs.GR binds to its sequences as an homodimer. Two different forms, GRa and GRb, differing in their C-terminal parts were isolated. GRa is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GRb does not bind glucocorticoids.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human GR alpha (2-60 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for NR3C1 Gene
- Nuclear Receptor Subfamily 3 Group C Member 1 2 3 4 5
- Glucocorticoid Receptor 2 3 4
- GR 2 3 4
- Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) 2 3
- GRL 3 4
- Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(54) 3
- Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(77) 3
- Nuclear Receptor Subfamily 3 Group C Member 1 Variant HGR-B(93) 3
- Nuclear Receptor Subfamily 3, Group C, Member 1 2
- Glucocorticoid Nuclear Receptor Variant 1 3
- GCRST 3
- NR3C1 5
- GCCR 3
- GCR 3
