HPR-labelled MAD Reagent

Cat. No.: FNK-BCL-MA-001
Long Term Storage: -20°C or below
Shipping Condition: Cold pack, ica pack, 4C  ( Do not use Dry-ice )

What is MAD reagent?
Our antibody binding Bionanocapsule (BNC) is about 55nm nanoparticle consisting of about 100 antibody-binding protein molecules. MAD（Multi Antibody Detection） reagent is the particle labelled with signal generating molecules. And useful for variety of immunoassays.

How MAD works?
MAD reagent bind to Fc region of antibodies, and little affect on the antigen-binding ability of antibodies. When mixed with antibodies, MAD reagent forms a complex with antibodies as shown in the right figure which displays Fab region on the particle surface. HRP-MAD reagent is made of BNC having 200 antibody binding sites and labelled with 100 HRP molecules per particle. Thus, MAD reagent has 50 times more labelled HRP and 100 times more antibody-binding sites than HRP-labeled IgGs, and shows much higher sensitivity. MAD can also used for one-step detection using the complex with antibdies.

 

Product #	Product Name	Product Outline	Content
BCL-DC-002	Bionanocapsule-ZZ (BNC-ZZ)	Antibody-binding BNC with protein A originated domain	100μg
BCL-MA-001	HRP-MAD reagent	HRP-labelled BNC-ZZ	100μg
BCL-MP-001	ALP-MAD reagent	ALP-labelled BNC-ZZ	100μg
BCL-MC-001 ～004	Fluorescent-MAD reagent	Cy2-, Cy3-, Cy5-, or Cy7-labelled BNC-ZZ (production by order)	*

Many ways to use Antibody-binding probes



Before you try to one of above applications please consult us. We will provide you advices or protocols. We provide kit products for Western (Easy-WESTERN) and ELISA (Easy ELISA constructor) using HRPlabelled MAD. Using these kits, all applications listed above for HRP-labelled MAD can be done.