Anti-ABHD2 Rabbit Polyclonal Antibody
Product#: SB-GB112406
$560.00
Availability:
Ships in 1-2 Weeks
Anti-ABHD2 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112406 |
| Size | ：100 uL |
| Protein full name | ：Monoacylglycerol lipase ABHD2 |
| Synonym | ：2-arachidonoylglycerol hydrolase, Abhydrolase domain-containing protein 2, Acetylesterase, Lung alpha/beta hydrolase 2, MmLABH2, Triacylglycerol lipase, Abhd2, Labh-2 |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse ABHD2 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：48 kDa |
| Observed MW. | ：55 kDa |
| Uniprot ID | ：Q9QXM0 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 | testis, lung |
Description
Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (By similarity). Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration .
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Western blot analysis of ABHD2 (GB112406) at dilution of 1: 1000 Lane 1: Mouse testis tissue lysate Lane 2: Mouse lung tissue lysate Lane 3: Rat testis tissue lysate Lane 4: Rat lung tissue lysate |
Aliases for ABHD2 Gene
- GeneCards Symbol: ABHD2 2
- Abhydrolase Domain Containing 2, Acylglycerol Lipase 2 3 5
- LABH2 2 3 4 5
- Abhydrolase Domain-Containing Protein 2 3 4
- 2-Arachidonoylglycerol Hydrolase 3 4
- Monoacylglycerol Lipase ABHD2 3 4
- Progesterone-Sensitive Lipase 3 4
- Lung Alpha/Beta Hydrolase 2 3 4
- Protein PHPS1-2 3 4
- Acetylesterase 3 4
- Alpha/Beta Hydrolase Domain Containing Protein 2 3
- Abhydrolase Domain Containing 2 2
- Testicular Tissue Protein Li 6 3
- EC 3.1.1.23 4
- EC 3.1.1.79 4
- EC 3.1.1'); 49
- EC 3.1.1.6 4
- EC 3.1.1 49
- PHPS1-2 3
- HS1-2 3