iMatrix-111 is a recombinant human laminin-111 E8 fragment protein expressed in Chinese Hamster Ovary (CHO)-S cells. iMatrix-111 contains the integrin-binding site of the laminin-111 molecule. iMatrix-111 is useful for differentiation of pluripotent stem cells into hepatic progenitor cells, hepatocytes, and neural cells iMatrix-111 also supports the culture of other cells adhering to laminin-111 such as neural cells.
Content: Recombinant human laminin-111 E8 fragment protein in 20 mM phosphate buffer, 250 mM NaCl
Protein concentration: 0.5 mg/mL
Amount: 350 μg / 2 tubes
Storage: Store at 2°C to 15°C, protect from light.
Expiration date: The shelf life is 2 years from the date of manufacture. The expiration date is printed on the carton.
References: Taniguchi Y. et al. (2009) J. Biol. Chem. 284 (12), 7820-31 Doi D. et al. (2014) Stem Cell Reports 2 (3), 337-50 Takayama K. et al. (2017) Hepatol. Commun. 1 (10), 1058-69 Kiyozumi D. et al. (2020) Life Sci. Alliance 3 (2), e201900515 Guo G. et al. (2021) Cell Stem Cell 28 (6), 1040-56
