Prodigiosin, 5mg
Product#: FNK-BLK-0560-5mg
$713.39
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Prodigiosin (5mg)
Cat No: FNK-BLK-0560-5mg
Product ID and Size
| Cat No. | Description | Size | Link |
| FNK-BLK-0560-100ug | Prodigiosin | 100μg |  |
| FNK-BLK-0560-1mg | Prodigiosin | 1mg | |
| FNK-BLK-0560-5mg | Prodigiosin | 5mg | |
Description
A marine bacterium, γ -proteobacterium strain MS-02-063 produces prodigiosins. The prodigiosins showed multibiological activities, antibacterial1) , antifungal2) , cytotoxic3) , antialgal activities4),5) , and inhibition of NADPH oxidase activation in macropharge6) . The prodigiosin induces apoptosis by phosphorylation of p38 MAP kinase. In addition, the prodigiosins inhibit the association of p47phox and Rac, which are NADPH oxidase cytosolic components, to the plasma membrane in macropharges.
Origin: γ-Proteobacterium hahella
CAS Registry Number: 82-89-3
CA Index Name: 4-Methoxy-5-[(5-methyl-4-pentyl-2H - pyrrol-2-ylidene)methyl]-2,2'-bi[1H - pyrrol]
Appearance: Dark red solid
Molecular Formula/ Weight: C20H25N3O=323.46
Melting Point: 120-122℃
Purity: 95>% by HPLC
Solubility: Sol. in MeOH, Chloroform, EtOH, EtOAc, Hexane, Acetone, Acetonitrile Insoluble in water
Handling and Storage: Store at -20℃. Protect from light
References:
- T. Nakashima, et al., Microbiol Immunol., 49, 407 (2005).
- T. Nakashima, et al., Infect Chemother, 11, 123 (2005).
- T. Nakashima, et al., Biological & Pharmaceutical Billetin. 28, 2289 (2005).
- T. Nakashima, et al., Appl. Microbiol.Biotechnol. 73, 684 (2006).
- T. Nakashima, et al., Aquat. Microb.Ecol. 45, 255 (2006).
- T. Nakashima, et al., J.Biochem. 143, 107 (2008).
