Polyoxin D,  5 X 1mg

Polyoxin D,  5 X 1mg


Cat. No.:  FNK-KK-300-5X1mg


Size 5 X 1mg

Storage 4°C

Origin Streptomyces cacaoi var.asoensis

M.W. 521.4

Purity 94.5%(HPLC)


Description

Polyoxin D is a nucleoside antibiotic from Streptomyces cacaoi var. asoensis, which is isolated from the soil in Aso area, Kumamoto prefecture (Japan). 14 of derivative is already known. Polyoxin D is a specific inhibitor of Chitin synthase in fungi.

Features of Polyoxin D

• Competitive inhibitor of Chitin synthase (EC 2.4.1.16) in fungi cell wall.
• Water soluble but insoluble in organic solvent such as Hexane or Acetone.

1. Isono K. et al., Agr. Biol. Chem., 31 (2), 190～199 (1967).
2. Ohta N. et al., Agr. Biol. Chem., 34 (8), 1224～1232 (1970).
3. Endo A. et al., J. Bact., 104 (1), 189～196 (1970).