Aplasmomycin A
Growth inhibition of Gram-positive bacteria; antimalarial activity in infected mice.
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Natural Macrocyclic Compounds from Microorganisms: Cyclic Peptides, Macrolides & More (IMC / BIKAKEN) | Diagnocine
Product#: Natural-Macrocyclic-Compounds-from-Microorganisms
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STRUCTURAL DIVERSITY RESEARCH
Natural Macrocyclic Compounds
From microorganisms — cyclic peptides, macrolides, macrolactams, and cyclic alkenes.
Research Use Only Institute of Microbial Chemistry (BIKAKEN) Distributed by Diagnocine
Natural products with macrocyclic architectures — cyclic peptides, macrolides, macrolactams, and cyclic alkenes — selected from the bioactive compounds of microbial origin discovered and isolated at the Institute of Microbial Chemistry (BIKAKEN). Defined by their distinctive ring systems, these molecules display intriguing biological activities and remain of strong interest to the research community.
12Research compounds
4Structural classes
IMCBIKAKEN origin
01
Macrolide
MACROLIDE
Migrastatin
Inhibition of cancer metastasis and of human small cell lung cancer cells.
02
Macrolactam
MACROLACTAMBisucaberin
Iron-chelating siderophore; induction of macrophage-mediated tumor cell lysis.
03
Cyclic Alkene
CYCLIC ALKENERubratoxin A
Competitive inhibition of protein phosphatase 2A (PP2A).
Ceramidustin
Pseudomonas aeruginosa ceramidase inhibitor.
04
Cyclic Peptide
CYCLIC PEPTIDEBottromycin A2
Activity demonstrated against Gram-positive bacteria, MRSA, and VRE.
Iturin A-2
Cytotoxicity against human breast cancer cells (BT-474).
Plipastatin A1
Inhibition of phospholipase A2; induction of systemic resistance (ISR).
Phepropeptin A
Inhibition of proteasome chymotrypsin-like activity.
Phepropeptin B
Inhibition of proteasome chymotrypsin-like activity.
Phepropeptin C
Inhibition of proteasome chymotrypsin-like activity.
Phepropeptin D
Inhibition of proteasome chymotrypsin-like activity.
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All 12 compounds are supplied for research use. Browse the full Diagnocine catalog or contact our team for availability, bulk quantities, and institutional or government purchasing.
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*Specifications are subject to change without notice.
Research Use Only. All products listed are intended for research use only and are not for use as pharmaceuticals, diagnostic agents, food, or food testing. Company and product names are trademarks or registered trademarks of the Institute of Microbial Chemistry. Compounds discovered and isolated by IMC (BIKAKEN); distributed in the United States by Diagnocine.
