Monoclonal Antibody Against HP Urease A (K2127B)
Product#: FNK-2AHPUA
$260.92
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Ships in 1-2 Weeks
Monoclonal Antibody Against HP Urease A (K2127B)
| Cat. No: | FNK-2AHPUA |
| Clone No: | Hyb-K2127B |
| Manufacturing Process: | Hybridoma obtained by fusing mouse myeloma cells (NS-1) with BALB/c mouse spleen cells immunized with urease derived from Helicobacter Pylori (HP) is proliferated in the BALB/c mouse abdominal cavity and ascites is collected. |
| Specificity: | This monoclonal antibody specifically reacts with HP urease small subunit (UreA). |
| Purification: | Ammonium sulfate precipitation. |
| Ig Class: | IgG1 |
| Form: | Saline (containing 0.1% NaN3) |
| Protein Concentration: | 0.5 mg/mL |
| Package: | 0.2 mL |
| Storage: | 2-8℃ (Below -20℃ for long term storage) |
| Application: | ELISA, IHC, Western blotting |
Antigen Characterization
| Type | : Enzyme |
| Application | : Urea hydrolysis, ammonia detection, soil analysis |
| Species | : Found in various bacteria, plants, and fungi |
| Recombinant | : Yes |
Urease A in the Cell
- Catalyzing urea hydrolysis: Urease A is part of the enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia. This reaction is crucial for nitrogen metabolism in many organisms.
- Bacterial virulence: In pathogenic bacteria, Urease A contributes to virulence by helping bacteria colonize and survive in host organisms. The ammonia produced by urease activity can neutralize acidic environments, allowing bacteria to persist in harsh conditions like the stomach.
- Nitrogen cycling in soil: In soil microorganisms, Urease A plays a role in the nitrogen cycle by breaking down urea from organic matter or fertilizers, releasing ammonia that can be used by plants or other microbes.
- Plant defense: In some plant species, Urease A may have additional functions beyond urea hydrolysis, including entomotoxicity (insect toxicity) and antifungal properties, potentially as part of a defense mechanism.
- Biomineralization: In certain microorganisms, Urease A contributes to the formation of calcium carbonate, which has potential applications in processes like creating bioconcrete.
- Diagnostic marker: The presence of Urease A is used as a diagnostic indicator for certain bacterial infections, particularly in gastrointestinal and urinary tract pathogens.
Aliases for Urease A Gene
- UreA
- Urease subunit alpha
- Urea amidohydrolase
