Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
UniProt accession
70,325
GeneID
6532
Synonyms
5HT transporter;5HTT;5-HTT;5-HTTLPR;HTT;OCD1;SERT;SERT1;SLC6A4;Sodium-dependent serotonin transporter;Solute carrier family 6 member 4
Gene names
SLC6A4
Research area
Others
Target protein
SLC6A4
Components
Components
Quantity
Pre-coated ELISA plate
12 * 8 well strips x1
Standard solution
0.5ml x1
Standard diluent
3ml x1
Streptavidin-HRP
6ml x1
Stop solution
6ml x1
Substrate solution A
6ml x1
Substrate solution B
6ml x1
Wash buffer concentrate (25x)
20ml x1
Biotinylated antibody
1ml x1
Protocol data
These standard curves of E6189Hu are provided for demonstration only. A standard
curve should be generated for each set of samples assayed.
Concentration
O.D.
Average
Corrected
6400ng/L
2.046
2.216
2.157
2.386
3200ng/L
1.173
1.277
1.218
1.381
1600ng/L
0.716
0.734
0.675
0.753
800ng/L
0.479
0.454
0.394
0.428
400ng/L
0.182
0.224
0.165
0.267
0ng/L
0.058
0.059
0
0.061
Precision
We measured random samples of E6189Hu within the same batch/lot to ensure the
consistency of the kits' performances.