Human Major Prion Protein, PRNP ELISA Kit

Product#: BTL-E5109Hu

$686.40

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Cat. No#: BTL-E5109Hu

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Product Summary

Size: ,96T

Sensitivity: 0.055ng/ml

Detection range: 0.1-40ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Major Prion Protein

SKU#.: ? BTL-	E5109Hu
Assay type	Sandwich
Size	0.055ng/ml
Detection range	0.1-40ng/ml
Sample type	Serum, plasma, cell culture supernates
Species	Human
Storage	2-8ºC
Assay time	1h 30m
Background	Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
UniProt accession	27,661
GeneID	5621
Synonyms	ASCR;CD antigen CD230;Major prion protein;PRNP;PrP;PrP27-30;PrP33-35C
Gene names	PRNP
Research area	Neuroscience
Target protein	PRNP

Components

Protocol data

These standard curves of E5109Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.