Anti-SOX2 Rabbit Polyclonal Antibody
Product#: SB-GB11249
$560.00
Availability:
Ships in 1-2 Weeks
Anti-SOX2 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB11249 |
| Size | ：100 uL |
| Protein full name | ：Transcription factor SOX-2 |
| Synonym | ：ANOP3, MCOPS3, SRY-box 2, Sox2 |
| Immunogen | ：KLH conjugated Synthetic peptide corresponding to Mouse SOX2 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Subcellular location | ：Nucleus |
| Uniprot ID | ：P48432, P48431 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| IHC | Human, Mouse, Rat | 1: 250-1: 800 |
fetal brain |
| IF | Human, Mouse, Rat | 1: 250-1: 800 | fetal brain |
Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
 |
Immunohistochemistry analysis of paraffin-embedded mice tumor with hela using SOX2 (GB11249) at dilution of 1:600 |
 |
Immunohistochemistry analysis of paraffin-embedded fetal rat brain using SOX2 (GB11249) at dilution of 1:600
|
Aliases for SOX2 Gene
- GeneCards Symbol: SOX2 2
- SRY-Box Transcription Factor 2 2 3 5
- SRY (Sex Determining Region Y)-Box 2 2 3
- Transcription Factor SOX-2 3 4
- SRY-Box 2 2 3
- Sex Determining Region Y-Box 2 3
- SRY-Related HMG-Box Gene 2 3
- Transcription Factor SOX2 3
- MCOPS3 3
- ANOP3 3
