Anti-NPDC1 Rabbit Polyclonal Antibody
Product#: SB-GB112503
$560.00
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Anti-NPDC1 Rabbit Polyclonal Antibody
General information
| Cat. No. | ：SB-GB112503 |
| Size | ：100 uL |
| Protein full name | ：Neural proliferation differentiation and control protein 1 |
| Synonym | ：NPDC-1, Npdc1, CAB1 |
| Immunogen | ：Recombinant protein corresponding to Mouse NPDC1 |
| Isotype | ：IgG |
| Purity | ：Affinity purification |
| Predicted MW. | ：36 kDa |
| Observed MW. | ：54 kDa |
| Uniprot ID | ：Q64322 |
| Storage | ：Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | ：PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Application
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 500-1: 1000 |
brain |
Description
NPDC-1 (Neural Proliferation Differentiation and Control-1) is expressed in neurons once they have stopped dividing and begun to differentiate. NPDC-1 is transported from the Golgi apparatus via vesicles before becoming internalized by endosomes at the cell membrane. NPDC-1 interacts with Cdk2, D-type cyclins, and the transcription factor E2F1. This interaction can lead to an increased replication time, and might have implications in final neural differentiation and apoptosis. NPDC-1 has been shown to colocalize with synaptic vesicle proteins: synaptophysin, synaptobrevin 2, and Rab3 GEP (Rab3 GTP/GDP exchange protein). One function of NPDC-1 is to regulate retinoic acid-mediated events by directly interacting with retinoid receptors.
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Western blot analysis of NPDC1 (GB112503) at dilution of 1: 1000 Lane 1: Mouse brain tissue lysate Lane 2: Rat brain tissue lysate |
Aliases for NPDC1 Gene
- GeneCards Symbol: NPDC1 2
- Neural Proliferation, Differentiation And Control 1 2 3 5
- CAB- 2 3 5
- CAB1 2 3 5
- Neural Proliferation Differentiation And Control Protein 1 3 4
- DKFZp586J0523 2 5
- NPDC-1 3 4
- CAB-1 3
- CAB 3