Anti Human RXR beta mouse monoclonal antibody (H7341)
RXR beta: Retinoid X Receptor beta
General information
| Cat. No. |
:FNK-PP-H7341-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human/ Rat |
| Purification |
:Ammonium sulfate fractionation. |
| Clone No |
:H7341 |
| Lot. |
:A-2 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Nomenclature |
:NR2B2 |
| Application |
:ELISA : 1 ug/mL (A450=1.0)
:Western Blot : 1 ug/mL
:Non reducing Western Blot : 1 ug/mL |
| Specificity |
:This antibody specifically recognizes human RXR beta and cross reacts with rat RXR beta. This antibody
does not recognize human RXR alpha and gamma. Not yet tested in other species.
|
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative |
| Genbank |
:M84820 |
Description
Retinoid X receptor beta (RXRb; NR2B2) is a member of orphan nuclear receptor. 9-cis retinoic acid can bind to RXR. RXRb is expressed widespread in most tissues of the embryo, including the central nerves system. Along with other members of the RXR family, RXRb plays roles in a variety of processes including embryonic patterning and organogenesis, cell proliferation and differentiation. RXRs commonly function as heterodimers with other members of the nuclear receptor superfamily.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RXR beta (9-187 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Nakamura T, et al., Nat Genet., 36(5): 528-33, 2004.
Aliases for RXRB Gene
- Retinoid X Receptor Beta 2 3 4 5
- Nuclear Receptor Subfamily 2 Group B Member 2 2 3 4
- NR2B2 2 3 4
- Retinoic Acid Receptor RXR-Beta 3 4
- H-2RIIBP 2 3
- RCoR-1 2 3
- MHC Class I Promoter Binding Protein 3
- Retinoid X Receptor, Beta 2
- DAUDI6 3
- RXRB 5