Anti Human RAR alpha mouse monoclonal antibody (H1920)
Product#: FNK-PP-H1920-00
$501.52
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Anti Human RAR alpha mouse monoclonal antibody (H1920)
RAR alpha: Retinoic Acid Receptor alpha
General information
| Cat. No. | ：FNK-PP-H1920-00 |
| Size | ：100 ul |
| Antigen Species | ：Human |
| Host Species | ：Mouse |
| Cross Reactivity | ：Human |
| Purification | ：Ammonium sulfate fractionation. |
| Clone No | ：H1920 |
| Lot. | ：A-1 |
| Concentration | ：1 mg/mL |
| Ig Class | ：G1 |
| Nomenclature | ：NR1B1 |
| Application | ：ELISA : 0.2 ug/mL ：Western Blot : 1 ug/mL ：Non reducing Western Blot: 3 ug/mL |
| Specificity |
：This antibody specifically recognizes human RAR alpha but does not recognize human RAR beta and gamma.
Not yet tested in other species. |
| Storage | ：Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form | ：Physiological saline with 0.1% NaN3 as a preservative |
| Genbank | ：X06614 |
Description
Retinoic acid receptor alpha (RARa; NR1B1) is closely related to TR. RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RARa is expressed in adult skin, lung. RARa is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control. The specific chromosomal translocation found in acute promyelocytic leukemia (APL), fuses the RARa gene to a gene called promyelocytes (PML).
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human RAR alpha (1-30 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Jun Qin, et al. Developmemtal Dynamics, 2007, 236: 810-820
Aliases for RARA Gene
- Retinoic Acid Receptor Alpha 2 3 4 5
- NR1B1 2 3 4
- Nuclear Receptor Subfamily 1 Group B Member 1 3 4
- RAR-Alpha 3 4
- RAR 2 3
- Nucleophosmin-Retinoic Acid Receptor Alpha Fusion Protein NPM-RAR Long Form 3
- Retinoic Acid Nuclear Receptor Alpha Variant 1 3
- Retinoic Acid Nuclear Receptor Alpha Variant 2 3
- Retinoic Acid Receptor, Alpha Polypeptide 3
- Retinoic Acid Receptor, Alpha 2
- RARA 5
