Anti Human PNR mouse monoclonal antibody (H7223)
PNR: Photoreceptor-specific Nuclear Receptor
General information
| Cat. No. |
:FNK-PP-H7223-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human/ Rat |
| Purification |
:Ammonium sulfate fractionation. |
| Clone No |
:H7223 |
| Lot. |
:A-1 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Nomenclature |
:NR2E3 |
| Application |
:ELISA : 10 ng/mL
:Western Blot : 1 ug/mL
:Immunohistochemistry : 10-20 μg/mL |
| Specificity |
:This antibody specifically recognizes human PNR and cross reacts with rat PNR. Not yet tested in
other species. |
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative |
| Genbank |
:AF121129 |
Description
Photoreceptor-specific nuclear receptor (PNR, RNR; NR2E3) is a member of orphan nuclear receptor. PNR is expressed in retina. PNR plays a role in retinal photoreceptor cell differentiation and degeneration.

Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human PNR (2-45 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Takezawa S, et al. The EMBO Journal 26, 764-774, 2007
Aliases for NR2E3 Gene
- Nuclear Receptor Subfamily 2 Group E Member 3 2 3 4 5
- PNR 2 3 4
- Photoreceptor-Specific Nuclear Receptor 3 4
- Retina-Specific Nuclear Receptor 3 4
- RP37 2 3
- RNR 3 4
- Rd7 2 3
- Nuclear Receptor Subfamily 2, Group E, Member 3 2
- NR2E3 5
- ESCS 3