Anti Human NGFI-B gamma mouse monoclonal antibody (H7833)
NGFI-B gamma: Nerve growth factor-induced clone B gamma
General information
| Cat. No. |
:FNK-PP-H7833-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human |
| Purification |
:Ammonium sulfate fractionation. |
| Clone No |
:H7833 |
| Lot. |
:A-1 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Nomenclature |
:NR4A3 |
| Application |
:ELISA : 1 ug/mL
:Western Blot : 1 ug/mL
:Immunoprecipitation : Decide by use |
| Specificity |
:This antibody specifically recognizes human NGFI-B gamma but does not recognize human NGFI-B alpha
and beta. Not yet tested in other species. |
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiological saline with 0.1% NaN3 as a preservative |
| Genbank |
:D78579 |
Description
Nerve growth factor inducible factor I-B gamma (NGFIBg, TEC, MINOR, CHN, NOR-1; NR4A3) is a member of orphan nuclear receptor. NGFI-Bg is expressed in skeletal muscle, fetal heart. Its expression is induced in response to various stress stimuli and growth factors. NGFI-Bg has roles in signaling in multiple tissues, including the hypothalamic-pituitary axis. RXR has been shown to be a partner for NR4A1 and NR4A2 but not NR4A3.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human NGFI-B gamma (2-95 aa).
Note
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Reference
- Takezawa S, et al. The EMBO Journal 26, 764-774, 2007
Aliases for NR4A3 Gene
- Nuclear Receptor Subfamily 4 Group A Member 3 2 3 4 5
- MINOR 2 3 4
- CSMF 2 3 4
- NOR1 2 3 4
- CHN 2 3 4
- Mitogen-Induced Nuclear Orphan Receptor 3 4
- Neuron-Derived Orphan Receptor 1 3 4
- Nuclear Hormone Receptor NOR-1 3 4
- Chondrosarcoma, Extraskeletal Myxoid, Fused To EWS 3
- Nuclear Receptor Subfamily 4, Group A, Member 3 2
- Translocated In Extraskeletal Chondrosarcoma 3
- NR4A3 5
- TEC 4