Anti Human DAX1 mouse monoclonal antibody (H7431)
DAX1: DSS-AHC critical region on the X chromosome, gene 1
General information
| Cat. No. |
:FNK-PP-H7431-00 |
| Size |
:100 ul |
| Antigen Species |
:Human |
| Host Species |
:Mouse |
| Cross Reactivity |
:Human |
| Purification |
:Ammonium sulfate fractionation |
| Clone No |
:H7431 |
| Lot. |
:A-2 |
| Concentration |
:1 mg/mL |
| Ig Class |
:G2a |
| Nomenclature |
:NR0B1 |
| Application |
:Western Blot (1 ug/mL)
:ELISA (0.6 ug/mL (A450=0.2)) |
| Specificity |
:This antibody specifically recognizes human DAX1. Not yet tested in other species.
|
| Storage |
:Store at 2 - 8 ºC up to one month. For long-term storage, the solution may be frozen in working aliquots.
Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended. |
| Form |
:Physiologic saline with 0.1 % NaN3 |
| Genbank |
:S74720 |
Description
DSS-AHC critical region on the X chromosome, gene 1 (DAX1, AHCH; NR0B1) is a member of orphan nuclear receptor. DAX1 is expressed in adrenal cortex, ovarian granulosa, theca cells, testicular Leydig cells, Sertoli cells, anterior pituitary gonadotrope cells and the neurons of the ventromedial nucleus of the hypothalamus. DAX1 involves in controlling development of the hypothalamic-pituitary axis, as well as in gonadal development and sex determination. DAX1 was shown to interact physically with SF-1.
Origin
Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human DAX1 (1-80 aa).
Notes
Sodium azide may react with lead and copper plumbing to form explosive metal azides. Flush with large amounts of water during disposal.
Aliases for NR0B1 Gene
- Nuclear Receptor Subfamily 0 Group B Member 1 2 3 4 5
- DAX1 2 3 4
- DSS-AHC Critical Region On The X Chromosome Protein 1 3 4
- Nuclear Receptor DAX-1 3 4
- AHCH 2 3
- AHC 3 4
- Truncated Nuclear Receptor Subfamily 0 Group B Member 1 3
- Nuclear Receptor Subfamily 0, Group B, Member 1 2
- Dosage-Sensitive Sex Reversal 2
- Nuclear Hormone Receptor 3
- DAX-1 3
- NROB1 3
- SRXY2 3
- NR0B1 5
- AHX 3
- DSS 3
- GTD 3
- HHG 3