Acid-PEG3-NHS ester

Acid-PEG3-NHS ester

 

• CAT Number : Gly-GMSL-118
• CAS Number : 1835759-79-9 
• Molecular Weight : 347.32
• Molecular Formula : C₁₄H₂₁NO₉
• Pack size: 1 g

Product Description: 
 Acid-PEG3-NHS ester is a non-cleavable linker for bio-conjugation containing an NHS group and a carboxylic acid group connected by a linear PEG chain. It is a versatile PEG derivative that increases solubility in aqueous media and is commonly used in various bioconjugation applications.

Property

• Molecular Formula: C₁₄H₂₁NO₉
• Molecular Weight: 347.32 g/mol
• CAS Number: 1835759-79-9
• Purity: 95-98%
• Physical State: Likely a solid at room temperature

Application and Usage

• Bioconjugation: Used to link proteins, peptides, or other biomolecules
• PROTAC synthesis: Serves as a linker in the development of Proteolysis Targeting Chimeras (PROTACs)
• Drug delivery: Potential use in the development of drug delivery systems
• Increasing aqueous solubility: The PEG spacer enhances solubility of conjugated molecules
• Protein modification: Can be used to modify proteins for various research applications

Safety and Handling

• Use appropriate personal protective equipment (PPE)
• Handle in a well-ventilated area
• Avoid skin contact and inhalation
• Store in a cool, dry place

Involved Human Diseases
While this compound is not directly associated with treating specific human diseases, its applications in bioconjugation, drug delivery, and PROTAC development may contribute to research and potential treatments for various conditions. However, no specific diseases are mentioned  for this particular compound.