Polyoxin D

Product#: KK-300
$55.00
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Polyoxin D

Cat. No. KK-300
Size 1mg
Storage 4°C
Origin Streptomyces cacaoi var.asoensis
M.W. 521.4
Purity 94.5%(HPLC)

Description

Polyoxin D is a nucleoside antibiotic from Streptomyces cacaoi var. asoensis, which is isolated from the soil in Aso area, Kumamoto prefecture (Japan). 14 of derivative is already known. Polyoxin D is a specific inhibitor of Chitin synthase in fungi.
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Features of Polyoxin D

  • Competitive inhibitor of Chitin synthase (EC 2.4.1.16) in fungi cell wall.
  • Water soluble but insoluble in organic solvent such as Hexane or Acetone.
Reference 
  1. Isono K. et al., Agr. Biol. Chem., 31 (2), 190~199 (1967).
  2. Ohta N. et al., Agr. Biol. Chem., 34 (8), 1224~1232 (1970).
  3. Endo A. et al., J. Bact., 104 (1), 189~196 (1970).
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