MonoSpin Ion Exchange Columns (SAX, SCX, C18-AX, C18-CX, CBA)

Product#: GL5011

Functional Group & Qty

  • SAX-50 pcs
  • SAX-100 pcs
  • SAX-L30 pcs
  • SCX-50 pcs
  • SCX-100 pcs
  • SCX-L30 pcs
  • C18AX-50 pcs
  • C18AX-100 pcs
  • C18CX-50 pcs
  • C18CX-100 pcs
  • CBA-50 pcs
  • CBA-100 pcs
  • CBA-L30 pcs
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MonoSpin Ion Exchange Columns (SAX, SCX, C18-AX, C18-CX, CBA)

MonoSpin is a monolithic SPE column excellent for the small volume sample with an easy and quick operation by centrifuge.


MonoSpin is a SPE (Solid Phase Extraction) column with monolithic silica (monolith). This is designed for small volume sample preparation by centrifuge. GL Sciences' unique monolith silica technology.
GL Sciences’ monolith silica technology has low-pressure, high-flow, and low-liquid-retention properties, makes it uniquely suited for handling small amount samples.


  • Easy-to-Operate
  • High Throughput and Rapid Operation for Biological Sample
  • Ideal for Small Sample Volumes
  • Selective Purification/Enrichment by Wide Various Functional Groups
S type (Short type) L type (Long type)
MonoSpin_fig2.png MonoSpin_fig3.png
Disc size : Φ 4.2 x 1.5 mm
Sample volume : up to 800 μL
Elution volume : 50 – 800 μL
Centrifuge : 2000 - 10000 x g
Disc size : Φ 9 x 3 mm
Sample volume : up to 8000 μL
Elution volume : 500 – 8000 μL
Centrifuge : 1000 x g

Functional Group
Cat. No. Image Functional Group Type Qty (pcs)

MonoSpin SAX

Trimethylaminopropyl has selection power by combining both strong anion exchange & weak hydrophobic interaction. This column is optimized for the extraction of acidic drugs and compounds from various biological samples.
SAX-50 pcs GLI_SAX-F2.png SAX S 50 
SAX-100 pcs SAX S 100
SAX-L30 pcs SAX L 30

MonoSpin SCX

Benzenesulfonic acid column is constructed to combine both strong cation exchange & hydrophobic interaction. This column is optimized for the extraction of drugs and compounds with basic properties. Various biological samples can be used.
SCX-50 pcs GLI_SCX-F2.png SCX S 50
SCX-100 pcs SCX S 100
SCX-L30 pcs SCX L 30

MonoSpin C18-AX

Octadecyl and trimethylaminopropyl are mixed together.  This column is optimized to provide high retention of acidic properties from samples such as serum samples with high salt. For pharmaceutical purposes, the colume is optimized for the recovery of acidic drugs and compounds with any acidic properties. 
C18AX-50 pcs GLI_C18-AX-F2.png C18AX S 50
C18AX-100 pcs C18AX S 100

MonoSpin C18-CX

Octadecyl and benzene sulfonic acid combined in column for both ion exchange & enhancing hydrophobic interaction . This column format is optimized for dissociating drugs and compounds with basic properties from various biological samples. This column provides high efficiency for cleaning up compound and is similar to C18 or SCX.
C18CX-50 pcs GLI_C18-CX-F2.png C18CX S 50
C18CX-100 pcs C18CX S 100

MonoSpin CBA

Carboxyl acid column is excellent for weak cation exchange purposes. This column is optimized for the extraction of drugs and compunds with basic properties in various biological samples.
CBA-50 pcs GLI_Ph-F1.png CBA S 50
CBA-100 pcs CBA S 100
CBA-L30 pcs CBA L 30


Example Data

Fig. 1 Purification of pyridylaminated saccharides (MonoSpin NH2)
MonoSpin NH2 shows up to 100% recovery of the pyridylaminated saccharides from original impure sample. 



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