Anti-LXR β, Human, Mouse-Mono (K8917)

Product#: PP-K8917-00
$577.00
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Anti-LXR β, Human, Mouse-Mono (K8917)

Cat. No. PP-K8917-00

Size 100ug
lyophilized antibody
Antigen- Human 
Host Animal- Mouse
Cross Reactivity- Human 
Application- ELISA, IP, Western Blot 
Unlabeled 
Purification- Pu
Clone- K8917
Class- IgG

Batch A2F1
Formulation Lyophilized from phosphate-buffered saline (PBS) containing 5% Trehalose as a stabilizer.
Ig Class G2a
Nomenclature NR1H2
Genbank U07132
Purification Ammonium sulfate fractionation.
Western Blot 2 ug/mL
Non-reducing Western Blot 2 ug/mL
ELISA 0.1 ug/mL
Immunoprecipitation Decide by use
Supershift Assay Not yet tested
Chromatin immunoprecipitation Not yet tested
Immunohistochemistry Not yet tested
Application / Recommended Concentration

In order to obtain the best results, optimal working dilutions should be determined by each individual user.

Store

Lyophilized samples are stable for twelve months when held at 2 - 8 C. Upon reconstitution, the antibody can be stored at 2 - 8 C up to one month. For long-term storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in a frost-free freezer is not recommended.

Description

Liver X receptor beta (LXRb, UR, NER, RIP15, OR -1; NR1H2) is a member of orphan nuclear receptor. LXRb is expressed in a wide variety of tissues (heart, liver, kidney, brain, testis, ovary, adrenal, uterus, prostate, vagina, lung, spleen). LXRs play important role in expression of ABC transporters. The protein is expressed as a 50 kDa nuclear form. LXRb forms heterodimer with RXR.

Origin

Produced in BALB/c mouse ascites after inoculation with hybridoma of mouse myeloma cells (NS-1) and spleen cells derived from a BALB/c mouse immunized with Baculovirus-expressed recombinant human LXR beta (2-86 aa).

Specificity

This antibody specifically recognizes human LXR beta but does not recognize human LXR alpha. This antibody does not cross react with rat LXR beta. Not yet tested in other species.

Reconsitution

Reconstitute with desired volume of distilled water. Reconstitution in 0.1 ml of distilled water yields an antibody concentration of 1mg/ml. Please note reconstituted solution will contain original PBS and 5% Treharose (see Formulation).

Reference 

  1. Watanabe Y, et al., Nuclear Receptor, 1: 1, 2003.
  2. Pavan L, et al., Endocrinology, 145(10): 4583-91, 2004.
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