Anti Mouse Rim1 Polyclonal Antibody

Product#: KO454
$522.57
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Anti Mouse Rim1 Polyclonal Antibody


General information 

Cat. No. KO454
Primary Source MGI:2152971
Type Polyclonal Antibody
Concentration 0.25 mg/mL
ContentsVolume 25 μg(100 μL/vial)
Gene ID 116837
Immunogen
Partial peptide of Mouse Rim1 N-terminal region
Purification Antigen Affinity
Source Rabbit Serum
Myeloma -
Clone number -
Isotype -
Buffer PBS [containing 2% Block Ace as a stabilizer,0.1% Proclin as a bacteriostat]
Cross Reactivity Rabbit
Label Unlabeled
Storage Store below –20 ℃. Once thawed, store at 4 ℃. Repeated freeze-thaw cycles should be avoided.
Synonyms Rim; RIM1; RIM1a; Serg1; Rab3ip1; KIAA0340; RIM1alpha; mKIAA0340; C030033M19Rik; Rims1
Application ELISA,WB,IP
 

ELISA

WB

IHC

ICC

IP

FCM

IF

Neutralization

1.0

1.0

Not tested

Not tested

5.0

Not tested

Not tested

Not tested

                                                                                                        (µg/mL)

 

UniPlot Summary

  • Function: Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity.
  • Sequence similarities: Contains 2 C2 domains. Contains 1 FYVE-type zinc finger. Contains 1 PDZ (DHR) domain. Contains 1 RabBD (Rab-binding) domain.


References

  1. KiyonakaS, et al. RIM1 confers sustained activity and neurotransmittervesicle anchoring to presynaptic Ca2+ channels. Nat Neurosci. 2007 Jun;10(6):691-701. *Application Reference
  2. Schoch S, et al. RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature. 2002 Jan 17;415(6869):321-6.

 

Aliases for RIMS1 Gene

  • Regulating Synaptic Membrane Exocytosis 1 2 3 5
  • RIM1 2 3 4
  • Regulating Synaptic Membrane Exocytosis Protein 1 3 4
  • Rab-3-Interacting Protein 2 3 4
  • KIAA0340 2 4
  • RAB3IP2 3 4
  • RIM 2 3
  • Rab-3-Interacting Molecule 1 4
  • Rab3-Interacting Molecule 1 3
  • RAB3 Interacting Protein 2 2
  • RAB3-Interacting Protein 2 3
  • Rab3-Interacting Molecule 2
  • CORD7 3
  • RIMS1 5
  • RIM 1 4

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