Anti Bovine NR5A1 Polyclonal Antibody

Product#: KO611
$565.00
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Anti Bovine NR5A1 Polyclonal Antibody


General information 

Cat. No. KO611
Category Development/Differentiation
Target NR5A1(SF-1)
Type Polyclonal Antibody
Concentration 0.25mg/ml
ContentsVolume 50μg (200μL/vial)
Gene ID 281948
Primary Source Ensembl:ENSBTAG00000009017
Immunogen
Recombinant protein of Bovine NR5A1 (full length) Raised in Rabbit
Purification Protein G
Source Rabbit Serum
Buffer PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat]
Cross Reactivity mouse
Label Unlabeled
Storage Store below –20℃. Once thawed, store at 4℃. Repeated freeze-thaw cycles should be avoided.
Application ELISA, WB, IHC, ICC, IP,IF


UniProt Summary

Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.
  

ELISA

WB

IHC

ICC

IP

FCM

IF

Neutralization

1.0

1.0-5.0

1.0-2.0

1.0-5.0

5.0-10

Not tested

1.0-5.0

Not tested

(µg/mL)

Reference

  1. Nomura M, et al: J. Biochem(1998) 124:217-224



Aliases for NR5A1 Gene

  • Nuclear Receptor Subfamily 5 Group A Member 1 2 3 4 5
  • Steroidogenic Factor 1 2 3 4
  • AD4BP 2 3 4
  • HSF-1 2 3 4
  • SF-1 2 3 4
  • SF1 2 3 4
  • Steroid Hormone Receptor Ad4BP 3 4
  • Fushi Tarazu Factor Homolog 1 3 4
  • FTZF1 3 4
  • STF-1 3 4
  • FTZ1 2 3
  • ELP 2 3
  • Nuclear Receptor Subfamily 5, Group A, Member 1 2
  • Steroidogenic Factor 1 Nuclear Receptor 3
  • Adrenal 4 Binding Protein 3
  • Adrenal 4-Binding Protein 4
  • Nuclear Receptor AdBP4 3
  • Steroidogenic Factor-1 3
  • SPGF8 3
  • SRXX4 3
  • SRXY3 3
  • NR5A1 5
  • POF7 3


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