Anti Bovine NR5A1 Polyclonal Antibody
Product#: KO611
$565.00
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Anti Bovine NR5A1 Polyclonal Antibody
General information
| Cat. No. | ：KO611 |
| Category | ：Development/Differentiation |
| Target | ：NR5A1(SF-1) |
| Type | ：Polyclonal Antibody |
| Concentration | ：0.25mg/ml |
| Contents（Volume） | ：50μg (200μL/vial) |
| Gene ID | ：281948 |
| Primary Source | ：Ensembl:ENSBTAG00000009017 |
| Immunogen |
：Recombinant protein of Bovine NR5A1 (full length) Raised in Rabbit
|
| Purification | ：Protein G |
| Source | ：Rabbit Serum |
| Buffer | ：PBS [containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat] |
| Cross Reactivity | ：mouse |
| Label | ：Unlabeled |
| Storage | ：Store below –20℃. Once thawed, store at 4℃. Repeated freeze-thaw cycles should be avoided. |
| Application | ：ELISA, WB, IHC, ICC, IP,IF |
UniProt Summary
Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1. The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.
|
ELISA |
WB |
IHC |
ICC |
IP |
FCM |
IF |
Neutralization |
|
1.0 |
1.0-5.0 |
1.0-2.0 |
1.0-5.0 |
5.0-10 |
Not tested |
1.0-5.0 |
Not tested |
(µg/mL)
Reference
- Nomura M, et al: J. Biochem(1998) 124：217-224
Aliases for NR5A1 Gene
- Nuclear Receptor Subfamily 5 Group A Member 1 2 3 4 5
- Steroidogenic Factor 1 2 3 4
- AD4BP 2 3 4
- HSF-1 2 3 4
- SF-1 2 3 4
- SF1 2 3 4
- Steroid Hormone Receptor Ad4BP 3 4
- Fushi Tarazu Factor Homolog 1 3 4
- FTZF1 3 4
- STF-1 3 4
- FTZ1 2 3
- ELP 2 3
- Nuclear Receptor Subfamily 5, Group A, Member 1 2
- Steroidogenic Factor 1 Nuclear Receptor 3
- Adrenal 4 Binding Protein 3
- Adrenal 4-Binding Protein 4
- Nuclear Receptor AdBP4 3
- Steroidogenic Factor-1 3
- SPGF8 3
- SRXX4 3
- SRXY3 3
- NR5A1 5
- POF7 3
